73059-36-6Relevant academic research and scientific papers
Copper-Catalyzed Benzylic C—H Functionalization, Oxidation and Cyclization of Methylarenes: Direct Access to 2-Arylbenzothiazoles
Yu, Wentao,Wu, Wanqing,Jiang, Huanfeng
, p. 1158 - 1166 (2019)
The direct C—H functionalization of methylarenes is of great significance. Herein, a copper-catalyzed oxidative C—N/C—S bond formation through benzylic C(sp3)—H functionalization, oxidation and cyclization of methylarenes is reported. Various 2-arylbenzothiazoles have been synthesized in moderate to excellent yields with readily available o-iodoaniline, potassium sulfide, and methylarenes as raw materials.
Controllable assembly of the benzothiazole framework using a CC triple bond as a one-carbon synthon
Huang, Yubing,Yan, Donghao,Wang, Xu,Zhou, Peiqi,Wu, Wanqing,Jiang, Huanfeng
supporting information, p. 1742 - 1745 (2018/02/21)
A concise and efficient protocol to assemble diverse benzothiazole derivatives in high yields was provided via copper catalyzed tandem cyclization with o-haloanilines, elemental sulfur and terminal alkynes as raw materials. In this protocol, C atoms on the CC triple bond were controllably involved in the construction of the benzothiazole framework and multiple carbon-heteroatom bonds through divergent routes.
