731-54-4Relevant academic research and scientific papers
Unexpected formation of 5-alkylidene derivatives of hydantoin from the Michael addition of 4-phenylurazole to fumaric esters
Soltanzadeh, Zahra,Imanzadeh, Gholamhassan,Noroozi-Pesyan, Nader,?ahin, Ertan,Hooshmand, Hemayat
, p. 1736 - 1741 (2016)
An unexpected reaction between 4-phenylurazole and fumaric esters which led to the formation of 5-alkylidene derivatives of hydantoin is described in this paper. The reaction takes place in the presence of tetrabutylammonium bromide (TBAB), and 1,4-diaza-
Action des hydroxyurees sur les maleate et fumarate de methyle. Obtention des carbomethoxy-5 oxa-6 dihydrouraciles; transposition en carbomethoxymethylene-5 hydantoines
Bennouna, Chakib,Petrus, Francoise,Verducci, Jean,Hauw, Christian,Gaultier, Jacques
, p. 2891 - 2897 (2007/10/02)
We describe in this paper the Michael-type addition of hydroxyureas with methyl maleate and fumarate.The cyclization of the ureidoxyester intermediates obtained leads to the isolation of 5-carbomethoxy 6-oxadihydrouracils; their structure is proved by X-ray analysis.These relatively unstable compounds undergo transposition under basic conditions and give 5-carbomethoxyhydantoins.
