731857-76-4

Upstream product

• 18276-85-2 diethyl 2-(4-methoxyphenyl)-2-oxoethylphosphonate 

Downstream Products

• 731857-77-5 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-octane-1-sulfonic acid 4-[6-(4-methoxy-phenyl)-2-phenyl-pyrimidin-4-yl]-phenyl ester 
• 67073-24-9 4-(4-methoxyphenyl)-2,6-bisphenylpyrimidine 

Relevant academic research and scientific papers

Palladium-catalyzed Buchwald-Hartwig type amination of fluorous arylsulfonates

Palladium-catalyzed cross-coupling reactions of aryl perfluorooctanesulfonates with amines are introduced. Application of the fluorous tag in multistep synthesis of triaryl-substituted pyrimidine is also described.

A traceless perfluorooctylsulfonyl tag for deoxygenation of phenols under microwave irradiation

The perfluorooctylsulfonyl group is introduced as a traceless tag for solution-phase palladium-catalyzed deoxygenation reactions. The synthetic efficiency is improved by microwave irradiation for reaction and fluorous solid-phase extraction for separation. Further application of this traceless tag for multistep synthesis of substituted hydantoin and pyrimidine is also described.