731860-40-5Relevant articles and documents
Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors
Hu, Baihua,Fan, Kristi Yi,Bridges, Kristie,Chopra, Rajiv,Lovering, Frank,Cole, Derek,Zhou, Ping,Ellingboe, John,Jin, Guixiang,Cowling, Rebecca,Bard, Jonathan
, p. 3457 - 3460 (2004)
A new series of bis-statine based peptidomimetic inhibitors of human β-secretase (BACE 1) was developed by structure-based modification of the three regions to the initial lead 3: an N-terminus, a central bis-statine core, and a C-terminus. Introduction o