73190-70-2

Usage

InChI:InChI=1/C18H15NO/c20-18(12-14-6-2-1-3-7-14)19-17-11-10-15-8-4-5-9-16(15)13-17/h1-11,13H,12H2,(H,19,20)

Upstream product

• 454713-45-2 naphthalen-2-yl-carbamic acid tert-butyl ester 
• 103-83-3 N,N'-dimethylbenzylamine 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 
• 201230-82-2 carbon monoxide 
• 91-59-8 naphthalen-2-ylamine 
• 103-82-2 phenylacetic acid 

Downstream Products

• 22440-24-0 3-benzyl-2H-benzo[f]quinazolin-1-one 
• 115916-74-0 N,N'-di-[2]naphthyl-2-phenyl-acetamidine 

Relevant academic research and scientific papers

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

Metal-free hydration of ynamides: Convenient approach to amides

The trifluoroacetic acid (TFA) mediated hydration of ynamides was developed, which is an efficient approach for the synthesis of N-monosubstituted amides. This convenient method is effective with a wide range of substrates under room temperature condition, and the products are obtained in high to excellent yields through an easy work-up process.

Triethyl phosphite-p-dimethylaminopyridine, a new reagent for direct syntheses of amides from aliphatic carboxylic acids and amines

Various amides have been prepared with high to moderate yields from the corresponding aliphatic carboxylic acids and amines using triethyl phosphite-p-dimethylaminopyridine as a new reagent and pyridine as solvent, at 100-110°C, for 12 hours.