73198-52-4Relevant academic research and scientific papers
Synthesis of dehydroamino acids and didehydrodioxopiperazines and their conversion into α-mercapto-α-amino acid derivatives
Herscheid, Jacobus D. M.,Scholten, Henk P. H.,Tijhuis, Marian W.,Ottenheim, Harry C. J.
, p. 73 - 78 (2007/10/02)
A synthesis of α,β-dehydroamino acid derivatives 12 is described, which is of possible general applicability and might be useful for the preparation of peptides which have such a moiety in their sequence.I addition, several didehydrodioxopiperazines (13-1
α-Functionalized Amino Acid Derivatives. A Synthetic Approach of Possible Biogenetic Importance
Herscheid, Jacobus D. M.,Nivard, Rutger J. F.,Tijhuis, Marian W.,Scholten, Henk P. H.,Ottenheijm, Harry C. J.
, p. 1880 - 1885 (2007/10/02)
A new and efficient approach of general applicability to the synthesis of α-functionalized α-amino acid derivatives 3 is described.It is based upon the proposal that the biosynthesis of such compounds might occur via oxidation of an N-acylated amino acid
