7320-53-8

Basic information

• Product Name: 4-METHYLDIBENZOFURAN
• Synonyms: 4-Methyldibenzo[b,d]furan;Dibenzofuran, 4-methyl-
• CAS NO: 7320-53-8
• Molecular Formula: C₁₃H₁₀O
• Molecular Weight: 182.22
• EINECS: 230-792-5
• Mol File: 7320-53-8.mol
• Article Data: 18

Chemical Properties

• Melting Point: 45℃
• Boiling Point: 306 °C at 760 mmHg
• Flash Point: 146 °C
• Appearance: /
• Density: 1.162 g/cm³
• Vapor Pressure: 0.00144mmHg at 25°C
• Refractive Index: 1.677
• CAS DataBase Reference: 4-METHYLDIBENZOFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLDIBENZOFURAN(7320-53-8)
• EPA Substance Registry System: 4-METHYLDIBENZOFURAN(7320-53-8)

Safety Data

• Hazardous Substances Data: 7320-53-8(Hazardous Substances Data)

Usage

General Description

4-Methyldibenzofuran is a naturally occurring organic compound with the molecular formula C13H10O. It's a polycyclic aromatic hydrocarbon that is considered to be a minor constituent of coal tar, which is a complex mixture of hundreds of different compounds. It is primarily used in research, for example in studies to quantify levels of airborne polycyclic aromatic hydrocarbons. Despite its low concentration in coal tar, 4-Methyldibenzofuran can also be synthesized in the laboratory for these specific research purposes. It is a combustible substance, which needs to be handled with care due to potential health and environmental hazards.

InChI:InChI=1/C13H10O/c1-9-5-4-7-11-10-6-2-3-8-12(10)14-13(9)11/h2-8H,1H3

Upstream product

• 74292-21-0 2,2'-dihydroxy-3-methyl-1,1'-diphenyl 
• 128916-11-0 2-Allyloxy-benzoic acid o-tolyl ester 
• 912824-85-2 2-(dibenzo[b,d]furan-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 74-88-4 methyl iodide 
• 512-56-1 trimethyl phosphite 
• 583-55-1 1-Bromo-2-iodobenzene 
• 3991-61-5 1-methyl-2-phenoxybenzene 
• 51412-72-7 dibenzo-[b,d]furan-4-carbonitrile 
• 1440730-08-4 2-(o-tolyloxy)phenyl pivalate 
• 26321-31-3 2-(p-tolyloxy)phenol 
• 615-37-2 ortho-methylphenyl iodide 
• 95-56-7 2-hydroxybromobenzene 
• 498-66-8 norbornene 
• 65344-26-5 4-Iododibenzo-[b,d]furan 

Downstream Products

• 96706-46-6 dibenzofuran-4-carbaldehyde 
• 17755-10-1 2-methyl-6-phenylphenol 

Relevant articles and documents

Palladium-Catalyzed Methylation of Aryl, Heteroaryl, and Vinyl Boronate Esters

A method for the direct methylation of aryl, heteroaryl, and vinyl boronate esters is reported, involving the reaction of iodomethane with aryl-, heteroaryl-, and vinylboronate esters catalyzed by palladium and PtBu2Me. This transformation occurs with a remarkably broad scope and is suitable for late-stage derivatization of biologically active compounds via the boronate esters. The unique capabilities of this method are demonstrated by combining carbon-boron bond-forming reactions with palladium-catalyzed methylation in a tandem transformation.

A One-Pot Synthesis of Dibenzofurans from 6-Diazo-2-cyclohexenones

A novel and efficient protocol for the rapid construction of dibenzofuran motifs from 6-diazo-2-cyclohexenone and ortho-haloiodobenzene has been developed. The process involves one-pot Pd-catalyzed cross-coupling/aromatization and Cu-catalyzed Ullmann coupling.

Efficient synthesis of dibenzoxaborininols from diaryl ethers and their application to dibenzofuran synthesis

A convenient and efficient method for the borylation of diaryl ethers leading to dibenzoxaborininols and the synthesis of dibenzofuran derivatives has been developed. The borylation involves the sequential three-step process: lithiation, borylation and hydrolysis. The synthesized dibenzoxaborininols could be readily transformed into dibenzofuran derivatives in good to excellent yields under palladium catalysis in the presence of iodine, and this is the first example for the formation of an aryl C-C bond from diarylborinic acids. Copyright