732278-69-2

Upstream product

• 81136-82-5 (E)-(R)-2-Amino-hex-4-enoic acid methyl ester 
• 121786-37-6 (E)-(R)-2-Amino-hex-4-enoic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 732278-75-0 3-(R)-but-2-enyl-2-oxo-5-(R),6-(S)-diphenyl-morpholine-4-carboxylic acid tert-butyl ester 
• 893403-31-1 (1S,2R,3S,7R)-2-methyl-5,9-dioxa-8-azatricyclo[5.2.1.0^3,8]decan-4-ol 
• 334994-38-6 2-(R)-tert-butoxycarbonylamino-hex-4-(E)-enoic acid 
• 334994-44-4 2-(S)-methyl-5-(S),9-(R)-dioxa-8-(S)-aza-tricyclo[5.2.1.0^3,8]decan-4-one 
• 334994-41-1 5-(R)-but-2-enyl-morpholin-2-one 
• 334994-42-2 (5R)-(but-2-enyl)-4-oxy-5,6-dihydro-[1,4]oxazin-2-one 
• 334994-40-0 2-(R,E)-aminohex-4-en-1-ol 

Downstream Products

• 732278-74-9 (5R,7S,8R,8aS)-7-Hydroxy-5-(1-hydroxy-2-nitro-ethyl)-2-(4-methoxy-benzyl)-8-methyl-hexahydro-imidazo[1,5-a]pyridin-3-one 
• 732278-70-5 (5S,7S,8R,8aS)-2-(4-methoxybenzyl)-8-methyl-5-(2-nitroethyl)-3-oxooctahydroimidazo[1,5-a]pyridin-7-yl acetate 
• 732278-68-1 7(S)-hydroxy-2(S)-(4-methoxy-benzyl)-8(S)-methyl-3-oxo-octahydro-imidazo[1,5-a]pyridine-5(R)-carbaldehyde 

Relevant academic research and scientific papers

Syntheses of the cylindrospermopsin alkaloids

An intramolecular 1,3-dipolar cycloaddition has efficiently constructed the A-ring portions of the cylindrospermopsin alkaloids. A nitro-aldol addition of an elaborated nitroalkane to a pyrimidine aldehyde followed by an intramolecular reductive guanidiny

A concise asymmetric synthesis of the marine hepatotoxin 7-epicylindrospermopsin

Born from a simple amino acid ... the potent hepatotoxic cyanobacterial alkaloid 7-epicylindrospermopsin (see picture) has been synthesized through a concise asymmetric eighteen-step route. An intramolecular 1,3-dipolar cycloaddition and a nitroaldol reac