732278-75-0Relevant academic research and scientific papers
Syntheses of the cylindrospermopsin alkaloids
Looper, Ryan E.,Runnegar, Maria T.C.,Williams, Robert M.
, p. 4549 - 4562 (2007/10/03)
An intramolecular 1,3-dipolar cycloaddition has efficiently constructed the A-ring portions of the cylindrospermopsin alkaloids. A nitro-aldol addition of an elaborated nitroalkane to a pyrimidine aldehyde followed by an intramolecular reductive guanidiny
A concise asymmetric synthesis of the marine hepatotoxin 7-epicylindrospermopsin
Looper, Ryan E.,Williams, Robert M.
, p. 2930 - 2933 (2007/10/03)
Born from a simple amino acid ... the potent hepatotoxic cyanobacterial alkaloid 7-epicylindrospermopsin (see picture) has been synthesized through a concise asymmetric eighteen-step route. An intramolecular 1,3-dipolar cycloaddition and a nitroaldol reac
