334994-44-4

Upstream product

• 334994-42-2 (5R)-(but-2-enyl)-4-oxy-5,6-dihydro-[1,4]oxazin-2-one 
• 81136-82-5 (E)-(R)-2-Amino-hex-4-enoic acid methyl ester 
• 334994-40-0 2-(R,E)-aminohex-4-en-1-ol 
• 334994-41-1 5-(R)-but-2-enyl-morpholin-2-one 
• 334994-38-6 2-(R)-tert-butoxycarbonylamino-hex-4-(E)-enoic acid 
• 732278-75-0 3-(R)-but-2-enyl-2-oxo-5-(R),6-(S)-diphenyl-morpholine-4-carboxylic acid tert-butyl ester 
• 121786-37-6 (E)-(R)-2-Amino-hex-4-enoic acid 
• 334994-39-7 ((E)-(R)-1-Hydroxymethyl-pent-3-enyl)-carbamic acid tert-butyl ester 
• 334994-43-3 (3S,5S,6R)-3-((E)-But-2-enyl)-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid tert-butyl ester 

Downstream Products

• 893403-38-8 (5R,7S,8R,8aS)-2-Benzyl-7-hydroxy-8-methyl-3-oxo-octahydro-imidazo[1,5-a]pyridine-5-carbaldehyde 
• 893403-29-7 (2S,3R,4S,6R)-2-(Benzylamino-methyl)-6-hydroxymethyl-3-methyl-piperidin-4-ol 
• 893403-35-5 (5R,7S,8R,8aS)-2-Benzyl-7-hydroxy-5-hydroxymethyl-8-methyl-hexahydro-imidazo[1,5-a]pyridin-3-one 
• 893403-33-3 (5R,7S,8R,8aS)-2-Benzyl-7-hydroxy-5-hydroxymethyl-8-methyl-hexahydro-imidazo[1,5-a]pyridine-3-thione 
• 732278-68-1 7(S)-hydroxy-2(S)-(4-methoxy-benzyl)-8(S)-methyl-3-oxo-octahydro-imidazo[1,5-a]pyridine-5(R)-carbaldehyde 
• 732278-69-2 (5R,7S,8R,8aS)-7-hydroxy-5-hydroxymethyl-2-(4-methoxybenzyl)-8-methylhexahydroimidazo[1,5-a]pyridin-3-one 
• 732278-74-9 (5R,7S,8R,8aS)-7-Hydroxy-5-(1-hydroxy-2-nitro-ethyl)-2-(4-methoxy-benzyl)-8-methyl-hexahydro-imidazo[1,5-a]pyridin-3-one 
• 732278-70-5 (5S,7S,8R,8aS)-2-(4-methoxybenzyl)-8-methyl-5-(2-nitroethyl)-3-oxooctahydroimidazo[1,5-a]pyridin-7-yl acetate 

Relevant academic research and scientific papers

A concise asymmetric synthesis of the marine hepatotoxin 7-epicylindrospermopsin

Born from a simple amino acid ... the potent hepatotoxic cyanobacterial alkaloid 7-epicylindrospermopsin (see picture) has been synthesized through a concise asymmetric eighteen-step route. An intramolecular 1,3-dipolar cycloaddition and a nitroaldol reac

Syntheses of the cylindrospermopsin alkaloids

An intramolecular 1,3-dipolar cycloaddition has efficiently constructed the A-ring portions of the cylindrospermopsin alkaloids. A nitro-aldol addition of an elaborated nitroalkane to a pyrimidine aldehyde followed by an intramolecular reductive guanidiny

Construction of the A-ring of cylindrospermopsin via an intramolecular oxazinone-N-oxide dipolar cycloaddition

The efficient synthesis of an A-ring synthon for the marine hepatatoxin cylindrospermopsin has been achieved. The key step features an intramolecular oxazinone N-oxide/alkene dipolar cycloaddition resulting in the establishment of the three contiguous ste