73243-10-4

Basic information

• Product Name: 4-S-cysteinylphenol
• Synonyms: 4-S-cysteinylphenol
• CAS NO: 73243-10-4
• Molecular Formula: C₉H₁₁NO₃S
• Molecular Weight: 0
• Mol File: 73243-10-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 434.7°C at 760 mmHg
• Flash Point: 216.7°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 2.51E-08mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 4-S-cysteinylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-S-cysteinylphenol(73243-10-4)
• EPA Substance Registry System: 4-S-cysteinylphenol(73243-10-4)

Safety Data

• Hazardous Substances Data: 73243-10-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO3S/c10-8(9(12)13)5-14-7-3-1-6(11)2-4-7/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

Upstream product

• 56-89-3 L-cystine 
• 108-95-2 phenol 
• 5147-00-2 O-acetyl-L-serine 
• 637-89-8 4-sulfanylphenol 
• 75893-04-8 Boc-Cys(Acm)(O)-OH 
• 407-41-0 L-phosphoserine 

Related news

Specific Incorporation of 4-S-cysteinylphenol (cas 73243-10-4) into Human Melanoma Cells07/13/2019

The incorporation of 4-S-cysteinylphenol (4-S-CP), a tyrosine analog, into malignant melanoma cells was evaluated. 4-S-CP was specifically incorporated into the melanotic melanoma cells (HMV-II), which have activity for melanin synthesis, but was scarcely incorporated into HeLA S3 or HMV-I cells...detailed

Mechanism of selective toxicity of 4-S-cysteinylphenol (cas 73243-10-4) and 4-S-cysteaminylphenol to melanocytes07/12/2019

Our previous studies showed that 4-S-cysteinylphenol (4-S-CP) and 4-S-cysteaminylphenol (4-S-CAP) inhibit the growth of malignant melanoma and cause depigmentation of black skin. In this study we examined kinetic constants of CP and CAP as substrates for tyrosinases and their properties as sulph...detailed

Relevant articles and documents

Expanding the Structural Diversity of Protein Building Blocks with Noncanonical Amino Acids Biosynthesized from Aromatic Thiols

Incorporation of structurally novel noncanonical amino acids (ncAAs) into proteins is valuable for both scientific and biomedical applications. To expand the structural diversity of available ncAAs and to reduce the burden of chemically synthesizing them, we have developed a general and simple biosynthetic method for genetically encoding novel ncAAs into recombinant proteins by feeding cells with economical commercially available or synthetically accessible aromatic thiols. We demonstrate that nearly 50 ncAAs with a diverse array of structures can be biosynthesized from these simple small-molecule precursors by hijacking the cysteine biosynthetic enzymes, and the resulting ncAAs can subsequently be incorporated into proteins via an expanded genetic code. Moreover, we demonstrate that bioorthogonal reactive groups such as aromatic azides and aromatic ketones can be incorporated into green fluorescent protein or a therapeutic antibody with high yields, allowing for subsequent chemical conjugation.

Synthesis and preliminary biodistribution of 3-iodo-4-hydroxyphenyl-L-cystein

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STUDIES ON PEPTIDES. XCVI. BEHAVIOR OF S-ACETAMIDOMETHYLCYSTEINE SULFOXIDE UNDER DEPROTECTING CONDITIONS IN PEPTIDE SYNTHESIS

The sulfoxide of Boc-Cys(S-acetamidomethyl)-OH was prepared by oxidation with sodium perborate.Mercuric acetate and iodine failed to cleave the S-protecting group from sulfoxide.Hydrogen fluoride and methanesulfonic acid partially converted the sulfoxide to S-p-methoxyphenylcysteine in the presence of anisole.A reducing reagent, thiophenol, converted the sulfoxide to acetamidomethyl phenyl sulfide and Nα-Boc-S-(phenylthio)cysteine.Keywords - S-acetamidomethylcysteine sulfoxide; mercuric acetate treatment; iodine treatment; hydrogen fluoride treatment; methanesulfonic acid treatment; thiophenol treatment