73251-32-8

Usage

Acetate ester of 2-(methylphenylamino)-2-oxoethanoic acid

This indicates the functional group of the compound, which is an ester formed from the reaction of the acid 2-(methylphenylamino)-2-oxoethanoic acid with acetic acid.

Intermediate in the synthesis of organic compounds

This shows the use of the compound as a starting material or building block in the production of other organic compounds.

Potential use as a building block in the production of pharmaceuticals, agrochemicals, and other fine chemicals

This highlights the potential applications of the compound in the production of various products.

Wide range of applications in the production of various products such as dyes, pigments, and polymers

This indicates the versatility of the compound in different industries.

Potential health hazards if not properly handled

This is a warning that the compound may pose a risk to human health if not handled and used in a controlled environment.

InChI:InChI=1/C11H13NO3/c1-9-4-2-3-5-10(9)12-8-11(14)15-7-6-13/h2-6,12H,7-8H2,1H3

Upstream product

• 100-61-8 N-methylaniline 
• 13831-31-7 Acetoxyacetyl chloride 
• 64-19-7 acetic acid 
• 2620-05-5 N-methyl-2-chloroacetanilide 
• 13831-30-6 acetoxyacetic acid 

Downstream Products

• 42404-09-1 2-hydroxy-N-methyl-N-phenylacetamide 

Relevant academic research and scientific papers

Method for preparing N-methyl-N-phenylacetamide acetate by one-pot method

The invention discloses a method for preparing N-methyl-N-phenylacetamide acetate by a one-pot method. The method comprises the following steps of (1) under a solvent-free state, dripping N-methylaniline into chloroacetyl chloride, heating to react after dripping is finished, removing hydrogen chloride, and cooling, so as to obtain N-methyl-N-phenylacetamide; (2) under the solvent-free state, directly adding acetic acid and a catalyst into the N-methyl-N-phenylacetamide obtained in the previous step, heating to react, removing the hydrogen chloride, preserving heat until the reaction is finished, and filtering, so as to obtain the N-methyl-N-phenylacetamide acetate, wherein the catalyst is a mixed catalyst of organic alkaline and quaternary ammonium salt. The preparation method has the advantages that a solvent is not used, the water washing is not needed, the green and environment-friendly effects are realized, only one reaction kettle is needed, and the cost is low.

Formation of N-heterocycles by the reaction of thiols with glyoxamides: Exploring a connective Pummerer-type cyclisation

The reaction of thiols with glyoxamides provides a convenient method for the generation of thionium ions and the initiation of Pummerer-type reactions. When the glyoxamides contain tethered aromatic nucleophiles, N-heterocycles are formed by a thionium ion cyclisation. The scope and mechanism of the connective Pummerer-type process has been investigated using a range of thiols, Lewis acids and both mono- and bis-glyoxamides. The utility of the process has been illustrated in a synthesis of the indoloquinoline natural product, neocryptolepine. The Royal Society of Chemistry 2009.

Benzothiazole substituted carboxylic acid amide compounds and herbicidal methods compositions thereof

Novel substituted carboxylic acid amide compound of the formula STR1 wherein n is an integer from 1 to 4 each R is independently selected from hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, amino, alkylamino, dialkylamino, nitro, cyano and alkoxycarbonyl; and two R radicals taken together can represent methylenedioxy, dichloromethylenedioxy or difluoromethylenedioxy, R1 is hydrogen or alkyl, R2 and R3 are individually selected from hydrogen or a radical selected from alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl, aryl and nitrogen-containing heterocycles, each of which radicals may be substituted and each of which radicals may, together with the nitrogen atom to which they are attached, form an optionally substituted, optionally partially unsaturated and optionally benzofused monocyclic or bicyclic radical, which may contain one or more further hetero-atoms, and X is oxygen or sulfur.

Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use

Therapeutic as well as preventive measures to alleviate the symptoms of dermatologic and other conditions and disorders with phenyl alpha-acyloxyacetamide derivatives is disclosed. Dermatologic and other conditions and disorders in humans in which the compounds may be useful include pruritus, atopic dermatitis, eczema, psoriasis, acne, dry skin, dandruff, malodors of integumental areas; and various aches, pains and discomforts of skin, joints and other body parts. The phenyl alpha-acyloxyacetamide derivatives include, for example, N-ethyl phenyl alpha-acetoxyacetamide, N-benzyl phenyl-alpha-acetoxyacetamide, N-phenethyl phenyl-alpha-acetoxyacetamide, N-benzyl diphenyl-alpha-acetoxyacetamide and N-phenethyl diphenyl-alpha-acetoxyacetamide. The compositions containing the active ingredients are also useful for treatment of skin conditions or disorders, and musculoskeletal disorders, of domestic animals, for example dogs, such as dry skin, scurf, eczema, mange, prurigo, malodors, arthritis or myositis. Some phenyl-alpha-acyloxyacetamide derivatives may have a tranquilizing effect.