73326-72-4Relevant academic research and scientific papers
Visible-light promoted γ-cyanoalkyl radical generation: Three-component cyanopropylation/etherification of unactivated alkenes
Li, Linyong,Chen, Haoguo,Mei, Mingjing,Zhou, Lei
, p. 11544 - 11547 (2017)
A photoredox approach to generate distal cyano-substituted alkyl radicals through C-C bond cleavage of cyclobutanone oximes was developed. The radicals produced by this method were applied to three-component cyanopropylation/etherification of unactivated alkenes. Their reactions with diverse radical acceptors were also demonstrated.
Beckmann fragmentation and successive carbon-carbon bond formation using Grignard reagents via phosphonium salt intermediates
Fujioka, Hiromichi,Matsumoto, Nao,Kuboki, Yuichi,Mitsukane, Hidenobu,Ohta, Reiya,Kimura, Takashi,Murai, Kenichi
, p. 718 - 722 (2016/07/19)
The intermediates formed during the Beckmann fragmentation of α-alkoxy and α-alkoxy-α-alkyl oxime acetates have been successfully trapped as phosphonium salts, which were subsequently reacted with a variety of Grignard reagents to give the corresponding s
Carbon-Carbon Bond-Formation via Ring-Opening between Cyclopropanes and Alkenes
Giese, Bernd,Zwick, Wolfgang
, p. 2526 - 2532 (2007/10/02)
Cyclopropanes 6 - 12 and alkenes 13 yield via methoxymercuration and reduction the products 14 - 20.The carbon-carbon bond-formation occurs under mild conditions because alkyl radicals 3 and 4 are intermediates in this synthesis.With electron-withdrawing substituents at alkenes 13 yields of 87 percent are reached (table 1).In these reactions mono- to tetrasubstituted cyclopropanes 6 - 12 can be used (table 2).
Methoxymercuration/demercuration reactions of cyclopropanes in the presence of acrylonitrile
Giese, Bernd,Zwick, Wolfgang
, p. 3569 - 3570 (2007/10/02)
Methoxymercuration/demercuration reactions of cyclopropanes 4 in the presence of acrylonitrile yield products 5 in a carbon-carbon bond formation reaction.
