73338-85-9

Upstream product

• 106120-04-1 5-bromoresorcinol 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 1459201-79-6 (2-hydroxy-4,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 1000773-37-4 3,5-bis(allyloxy)benzoic acid chloride 
• 268232-78-6 (1-(3,5-bis((tert-butyldimethylsilyl)oxy)phenyl)ethanone) 
• 51863-60-6 3,5-dihydroxyacetophenone 
• 14382-91-3 2-hydroxy-4,5-dimethoxybenzaldehyde 
• 185254-52-8 3,5-bis(allyloxy)benzoic acid 

Relevant academic research and scientific papers

Preparation method of benzofuran compound

The invention discloses a preparation method of a benzofuran compound. The preparation method comprises a step of subjecting a compound with a structure as shown in a formula (I) which is described inthe specification to a reacting in the presence of a ca

Deconstructive Reorganization: De Novo Synthesis of Hydroxylated Benzofuran

An unprecedented deconstructive reorganization strategy for the de novo synthesis of hydroxylated benzofurans from kojic acid- or maltol-derived alkynes is reported. In this reaction, both the benzene and furan rings were simultaneously constructed, whereas the pyrone moiety of the kojic acid or maltol was deconstructed and then reorganized into the benzene ring as a six-carbon component. Through this strategy, at least one free hydroxyl group was introduced into the benzene ring in a substitution-pattern tunable fashion without protection–deprotection and redox adjustment. With this method, a large number of hydroxylated benzofuran derivatives with different substitution-patterns have been prepared efficiently. This methodology has also been shown as the key step in a collective total synthesis of hydroxylated benzofuran-containing natural products (11 examples).

Synthesis of Benzo[ b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogues, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Synthetic method for moracin F using Suzuki coupling reaction

An objective of the present invention is to provide a method for synthesizing a natural compound moracin F having biological activity. Inventors of the present invention can efficiently synthesize moracin F having biological activity by using Suzuki coupl

Synthetic method for moracin F using Sonogashira coupling reaction

The present invention relates to a method for synthesizing a natural compound, moracin F having biological activity. The synthesis method of the present invention can efficiently synthesize the moracin F having biological activity by using Sonogashira cou

Synthetic method for moracin F using intramolecular Wittig reaction

The present invention provides a method for synthesizing a natural compound moracin F having biological activity. When using the method of the present invention, moracin F having a biological activity can be effectively synthesized by using an intramolecu

Diversity oriented synthesis of natural 2-arylbenzofuran, moracin F

Diversity oriented synthesis of natural 2-arylbenzofuran, moracin F (1) has been carried out from the commercially available starting materials using Sonogashira coupling, Suzuki coupling, neutral Al2O3 mediated cyclization, and intr