733748-92-0

Basic information

• Product Name: 4-(3-ISOPROPYL-1,2,4-OXADIAZOL-5-YL)PIPERIDINE
• Synonyms: 3-Isopropyl-5-(piperidin-4-yl)-1,2,4-oxadiazole;4-(3-Isopropyl-1,2,4-oxadiazol-5-yl)piperidine;4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine(SALTDATA: HCl)
• CAS NO: 733748-92-0
• Molecular Formula: C₁₀H₁₇N₃O
• Molecular Weight: 195.26
• Mol File: 733748-92-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 316.9°C at 760 mmHg
• Flash Point: 145.5°C
• Appearance: /
• Density: 1.049g/cm³
• Vapor Pressure: 0.000397mmHg at 25°C
• Refractive Index: 1.4860
• Storage Temp.: 2-8°C
• PKA: 9.58±0.10(Predicted)
• CAS DataBase Reference: 4-(3-ISOPROPYL-1,2,4-OXADIAZOL-5-YL)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-ISOPROPYL-1,2,4-OXADIAZOL-5-YL)PIPERIDINE(733748-92-0)
• EPA Substance Registry System: 4-(3-ISOPROPYL-1,2,4-OXADIAZOL-5-YL)PIPERIDINE(733748-92-0)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 733748-92-0(Hazardous Substances Data)

Usage

General Description

4-(3-Isopropyl-1,2,4-oxadiazol-5-yl)piperidine is a chemical compound with the molecular formula C13H22N4O. It is a piperidine derivative with a substituted oxadiazole ring, and it is commonly used in organic synthesis and pharmaceutical research. The compound has potential pharmaceutical applications due to its ability to act as a central nervous system stimulant, and it may have potential as a therapeutic agent for various neurological disorders. 4-(3-Isopropyl-1,2,4-oxadiazol-5-yl)piperidine is also used as a building block or intermediate in the synthesis of other organic compounds, making it an important chemical in the field of medicinal chemistry and drug development.

InChI:InChI=1/C10H17N3O/c1-7(2)9-12-10(14-13-9)8-3-5-11-6-4-8/h7-8,11H,3-6H2,1-2H3

Upstream product

• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 913264-42-3 tert-butyl 4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate 

Downstream Products

• 1310693-19-6 C₂₂H₂₅N₇O₃S 
• 733748-89-5 4-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-6-(4-methanesulfonyl-phenoxy)-pyrimidine-5-carbonitrile 
• 733751-18-3 4-(2,5-difluoro-phenylamino)-6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-pyrimidine-5-carbonitrile 
• 733751-17-2 4-(2,3-difluoro-phenylamino)-6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-pyrimidine-5-carbonitrile 
• 733749-86-5 1-[4-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-6-(4-methanesulfonyl-phenoxy)-pyrimidin-5-yl]-ethanone 
• 733749-84-3 4-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-6-(4-methanesulfonyl-phenoxy)-2-methyl-pyrimidine-5-carbonitrile 

Relevant articles and documents

NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a triazolone derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The triazolone derivative or its pharmaceutically acceptable salt can effectively activate GPR119; and therefore be usefully applied for preventing or treating diabetes mellitus.

NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS

The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.