7340-19-4

Upstream product

• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 3532-25-0 N-benzyloxy benzamide 
• 98-09-9 benzenesulfonyl chloride 
• 622-33-3 N-benzyloxyamine 

Downstream Products

• 1355362-45-6 4-[N-(benzyloxy)-N-benzenesulfonamide]butan-2-one 
• 1355362-44-5 methyl 3-[N-(benzyloxy)-N-benzenesulfonyl]propanoate 
• 1355362-46-7 3-[N-(benzyloxy)-N-benzenesulfonamide]-1-phenylpropan-1-one 

Relevant academic research and scientific papers

O-Substituted N-oxy arylsulfinamides and sulfonamides in Michael reactions

O-Substituted N-oxy arylsulfinamides and sulfonamides undergo fast aza-Michael reaction in the presence of base and electron-deficient α,β-unsaturated olefins under mild conditions. With N-silyloxy benzenesulfinamides, no aza-Michael product is observed and a hetero aza-Brook type rearrangement takes place induced by the base. Room temperature N-desulfinylation of N-benzyloxybenzenesulfinamide is achieved using BF 3.Et2O. N-Alkoxy arylsulfonamides aza-Michael adducts are found to be generally highly stable under strongly acidic and basic conditions.

Reactions of N-Acyl-O-arylhydroxylamines: Part IV - Preparation of Some N-Arylsulphonyl-O-arylhydroxylamines

A number of N-arylsulphonyl-O-alkylhydroxylamines (III) have been prepared by condensing appropriate alkoxyamines with arylsulphonyl chlorides in the presence of a base.The alkoxyamines have been obtained from the corresponding alkoxyamine hydrochlorides or hydrobromides (II) which in turn have been prepared by the hydrolysis of appropriate N-benzoyl-O-alkylhydroxylamines (I) with ethanolic hydrogen chloride or hydrogen bromide.The structure assignments of III are based on elemental analyses, chemical reaction and spectral (IR, PMR) data.