73410-07-8

Upstream product

• 87802-43-5 4,4-dimethyl-5,5-(ethylenedioxy)-1-pentene 
• 104730-31-6 2-(4-hydroxy-1,1-dimethylbutyl)-1,3-dioxolane 
• 147377-61-5 4-(1,3-dioxolan-2-yl)-1-iodo-4-methylpentane 
• 680614-41-9 5-iodo-2,2-dimethylpentanal 
• 122471-54-9 3,3-Dimethyl-6-iodo-1-hexyne 
• 1610839-59-2 dimethyl 2-(4,4-dimethylhex-5-ynyl)malonate 
• 1610839-57-0 dimethyl 3,3-dimethyl-2-methylenecyclohexane-1,1-dicarboxylate 
• 1610839-55-8 C₁₂H₁₈O₄ 
• 5497-67-6 2,2-dimethyl-4-pentenal 

Downstream Products

• 157552-28-8 iso-β-cyclocitral 

Relevant academic research and scientific papers

Preparation of chiral building blocks for the enantioselective total synthesis of ent-kauranoids by the pig liver esterase-catalyzed asymmetric hydrolysis of a dialkyl malonate-type prochiral diester

The preparation of chiral building blocks, suitable for use in the enantioselective total synthesis of kauranoids and ent-kauranoids, is reported herein. The pig liver esterase-catalyzed asymmetric hydrolysis of dimethyl 3,3-dimethyl-2-methylenecyclohexane-1,2-dicarboxylate, a malonate-type prochiral diester, afforded the corresponding half-ester in 96% yield and with 99% enantiomeric excess. The absolute configuration of the half-ester was determined by X-ray crystallographic analysis of its derivative and its enantiodivergent transformations are also described herein.

Cyclic terpenoid onium salts, their preparation and uses

Acyclic terpenoid onium salts are cyclized in an acidic aqueous solution at a temperature of at least about 80° C.