73437-07-7Relevant academic research and scientific papers
Condensed Isothiazoles. Part 7. Substitution Reactions of 3-Methyl-1,2-benzisothiazole and Some of Its 4- and 5-Substituted Derivatives
Clarke, Kenneth,Gleadhill, Brian,Scrowston, Richard M.
, p. 2845 - 2866 (2007/10/02)
Some electrophilic substitution reactions of 3-methyl-1,2-benzisothiazole and its 4-bromo-, 5-acetamido-, 5-amino, 5-bromo-, 5-hydroxy-, and 5-methoxy-derivatives are described. 4-Chloro, 4-bromo-, 4,6-dibromo- and 4-nitro-3-methyl-1,2-benzisothiazole may be obtained by deamination of the appropriate substitution products of 5-amino-3-methyl-1,2-benzisothiazole.Improved syntheses of 7-chloro- and 7-bromo-3-methyl-1,2-benzisothiazole have been achieved.
