73511-58-7

Upstream product

• 148-24-3 8-quinolinol 
• 65625-13-0 N-phenyl-2-[2-((quinolin-8-yloxy)acetyl)hydrazine-1-carbothioamide] 
• 42322-30-5 ethyl 2-(quinolin-8-yloxy)acetate 
• 3281-08-1 8-quinolinoxyacetic acid hydrazide 

Downstream Products

• 73511-70-3 2-((4-phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid 

Relevant academic research and scientific papers

Synthesis of some novel 3,4,5-trisubstituted triazole derivatives bearing quinoline ring and evaluation of their antimicrobial activity

Some new 3,4,5-trisubstituted 1,2,4-triazole derivatives were synthesized and studied for their antimicrobial activity. The lead compounds were obtained starting from 8-hydroxyquinoline and ethyl 2-chloroacetate. The obtained ester compound (1) first reac

Regioselective synthesis, antitumor and antioxidant activities of some 1,2,4-triazole derivatives based on 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol

Regioselective synthesis of some triazole derivatives 4–18 was achieved from the versatile, readily accessible 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3. The structures of the newly synthesized products were confirmed and characterized by IR, 1H NMR, 13C NMR, and mass spectral studies. Most of the synthesized compounds were evaluated for their antitumor and antioxidant activities and demonstrated potent to weak activities.