73515-08-9

Basic information

• Product Name: 1-(4-iodobutyl)-4-methoxybenzene
• CAS NO: 73515-08-9
• Molecular Formula: C₁₁H₁₅IO
• Molecular Weight: 290.1407
• Mol File: 73515-08-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 320°C at 760 mmHg
• Flash Point: 147.4°C
• Density: 1.464g/cm³
• Vapor Pressure: 0.00061mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 1-(4-iodobutyl)-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-iodobutyl)-4-methoxybenzene(73515-08-9)
• EPA Substance Registry System: 1-(4-iodobutyl)-4-methoxybenzene(73515-08-9)

Safety Data

• Hazardous Substances Data: 73515-08-9(Hazardous Substances Data)

Usage

General Description

1-(4-iodobutyl)-4-methoxybenzene is an organic compound with the chemical formula C11H15IO. It is a benzene derivative with a butyl group substituted at the 1 position and a methoxy group substituted at the 4 position. The presence of an iodine atom in the molecule gives it a higher molecular weight and a higher reactivity. 1-(4-iodobutyl)-4-methoxybenzene is commonly used in chemical synthesis and as a building block for the preparation of various pharmaceuticals and organic compounds. It has also been studied for its potential use in organic electronic devices and as a target for medicinal chemistry research.

Upstream product

• 288-32-4 1H-imidazole 
• 52244-70-9 4-(4-methoxyphenyl)butan-1-ol 
• 35191-43-6 1-(4-bromo-butyl)-4-methoxy-benzene 

Downstream Products

• 153748-36-8 3-[4-(4-Methoxyphenyl)butyloxy]-6-methyl-2-pyridine carboxaldehyde 
• 108185-82-6 4-(4-Nitro-butyl)-phenol 
• 864156-80-9 [6-(4-methoxy-phenyl)-hex-1-ynyl]-trimethyl-silane 
• 1027977-09-8 3-{6-(2-Methoxycarbonyl-ethyl)-5-[4-(4-methoxy-phenyl)-butoxy]-pyridin-2-ylmethylsulfanylmethyl}-benzoic acid methyl ester 
• 1026812-51-0 3-{6-((E)-2-Methoxycarbonyl-vinyl)-5-[4-(4-methoxy-phenyl)-butoxy]-pyridin-2-ylmethylsulfanylmethyl}-benzoic acid methyl ester 
• 1025972-13-7 3-{6-Hydroxymethyl-3-[4-(4-methoxy-phenyl)-butoxy]-pyridin-2-yl}-propionic acid methyl ester 
• 170569-18-3 (E)-3-{3-[4-(4-Methoxy-phenyl)-butoxy]-6-methyl-1-oxy-pyridin-2-yl}-acrylic acid methyl ester 
• 170569-19-4 (E)-3-{6-Hydroxymethyl-3-[4-(4-methoxy-phenyl)-butoxy]-pyridin-2-yl}-acrylic acid methyl ester 
• 170569-17-2 (E)-3-{3-[4-(4-Methoxy-phenyl)-butoxy]-6-methyl-pyridin-2-yl}-acrylic acid methyl ester 
• 134304-39-5 1-Methoxy-4-(4-nitro-butyl)-benzene 

Relevant articles and documents

Fluorination Triggers Fluoroalkylation: Nucleophilic Perfluoro-tert-butylation with 1,1-Dibromo-2,2-bis(trifluoromethyl)ethylene (DBBF) and CsF

Perfluoro-tert-butylation reaction has long remained a challenging task. We now report the use of 1,1-dibromo-2,2-bis(trifluoromethyl)ethylene (DBBF) as a practical reagent for perfluoro-tert-butylation reactions for the first time. Through a consecutive triple-fluorination process with DBBF and CsF, the (CF3)3C? species can be liberated and observed, which is able to serve as a robust nucleophilic perfluoro-tert-butylating agent for various electrophiles. The power of this synthetic protocol is evidenced by the efficient synthesis of structurally diverse perfluoro-tert-butylated molecules. Multiple applications demonstrate the practicability of this method, as well as the superiority of perfluoro-tert-butylated compounds as sensitive probes. The perfluoro-tert-butylated product was successfully applied in 1H- and 19F-magnetic resonance imaging (MRI) experiment with an ultra-low field (ULF) MRI system.

Azole derivatives

Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, are disclosed. Also disclosed are methods of preparation of the above-mentioned compounds, pharmaceutical compositions and salts and esters

Novel oxidized thioether derivatives

The present invention provides the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them