735271-93-9Relevant academic research and scientific papers
Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: Design, synthesis, and preclinical characterization
Elokdah, Hassan,Abou-Gharbia, Magid,Hennan, James K.,McFarlane, Geraldine,Mugford, Cheryl P.,Krishnamurthy, Girija,Crandall, David L.
, p. 3491 - 3494 (2007/10/03)
Indole oxoacetic acid derivatives were prepared and evaluated for in vitro binding to and inactivation of human plasminogen activator inhibitor-1 (PAI-1). SAR based on biochemical, physiological, and pharmacokinetic attributes led to identification of tip
