73550-56-8

Usage

Uses

Used in Pharmaceutical Development:
2-AZABICYCLO[2.1.1]HEXANE-1-CARBOXYLIC ACID is used as a potential pharmacological agent for targeting the central nervous system due to its effects on this system. This makes it a candidate for drug development, particularly for conditions related to the central nervous system.
Used in Organic Chemistry:
In the field of organic chemistry, 2-AZABICYCLO[2.1.1]HEXANE-1-CARBOXYLIC ACID is used as a building block in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and properties allow it to be a valuable component in creating new and effective molecules for a range of applications.

InChI:InChI=1/C6H9NO2/c8-5(9)6-1-4(2-6)3-7-6/h4,7H,1-3H2,(H,8,9)

Upstream product

• 77422-36-7 2-Acetyl-2-aza-bicyclo[2.1.1]hexane-1-carboxylic acid ethyl ester 
• 77422-38-9 methyl N-benzoyl-1-azabictclo<2.3.1>hexane-5-carboxylate 
• 77422-35-6 2-(Acetyl-allyl-amino)-acrylic acid ethyl ester 
• 77422-37-8 methyl N-allyl-2-benzamidopropenoate 
• 421580-30-5 syn-2-[(benzyloxy)methyl]-5,7-diazaspiro[3.4]octane-6,8-dione 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 
• 172324-66-2 3-(benzyloxymethyl)-2,2-dichlorocyclobutanone 

Downstream Products

• 127926-24-3 2-(tert-butoxycarbonyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid 
• 103794-05-4 2-Aza-bicyclo[2.1.1]hexane-1-carboxylic acid benzyl ester; compound with toluene-4-sulfonic acid 
• 103794-07-6 2,4-MePro-NHMe 
• 103794-06-5 2-Acetyl-2-aza-bicyclo[2.1.1]hexane-1-carboxylic acid benzyl ester 
• 103794-09-8 L-Tyr-2,4-MePro-NHMe 
• 103794-03-2 Ac-L-Tyr-2,4-MePro-NHMe 
• 103794-08-7 Boc-L-Tyr-2,4-MePro-NHMe 
• 103794-02-1 Ac-2,4-MePro-NHMe 
• 73550-55-7 Cis-ACBD 
• 116129-05-6 methyl 2,4-methanopyroglutamate 
• 116129-01-2 N-(t-butoxycarbonyl)-1-carbomethoxy-2-azabicyclo[2.1.1]hexane 
• 109794-96-9 cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid 

Relevant academic research and scientific papers

A new and short method for the synthesis of 2,4-methanoproline

2,4-Methanoproline, a supposed non-proteinogenic anti-feedant, was synthesised in 5 steps starting from allyl benzyl ether 3 in 10% overall yield with an intramolecular nucleophilic substitution as the key step for the formation of the bicyclic skeleton.

Total Synthesis of Cyclobutane Amino Acids from Atelia herbert smithii

The syntheses of two amino acids from the seeds of the legume Atelia herbert smithii, 2,4-methanoproline and 2,4-methanoglutamic acid, are described.The synthesis of third amino acid, cis-1-amino-3-(hydroxymethyl)cyclobutanecarboxylic acid and subsequent

TOTAL SYNTHESIS OF 2,4-METHANOPROLINE

The total synthesis of 2,4-methanoproline is achieved utilizing as the key step an intramolecular photocycloaddition.

SYNTHESIS OF 2,4-METHANOPROLINE

An efficient synthesis of 2,4-methanoproline from serine is described.The cyclobutane is formed by a sensitized intramolecular photoaddition.