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Usage

Uses

Used in Pharmaceutical Industry:
3-[3-(chlorosulfonyl)phenyl]sulfonylbenzenesulfonyl chloride is used as an intermediate in the synthesis of pharmaceutical compounds for the treatment of various diseases. Its unique chemical structure allows it to be a versatile building block in the development of new drugs.
Used in Chemical Synthesis:
In the chemical industry, 3-[3-(chlorosulfonyl)phenyl]sulfonylbenzenesulfonyl chloride is used as a reagent in the synthesis of various organic compounds. Its ability to form sulfonyl linkages makes it a valuable component in the creation of complex molecules.
Used in Research and Development:
3-[3-(chlorosulfonyl)phenyl]sulfonylbenzenesulfonyl chloride is utilized in research laboratories for the study of chemical reactions and the development of new synthetic methods. Its unique properties make it an interesting subject for scientific investigation.
Used in Antimicrobial Applications:
As a derivative of 4,4’-Dichlorodiphenyl Sulfone, which is an antibacterial agent, 3-[3-(chlorosulfonyl)phenyl]sulfonylbenzenesulfonyl chloride has potential applications in the development of new antimicrobial agents. It can be used to combat bacterial infections, particularly in the treatment of dermatitis herpetiformis.

Upstream product

• 71-43-2 benzene 
• 127-63-9 diphenyl sulphone 

Downstream Products

• 911065-84-4 C₂₀H₂₈N₂O₆S₃ 
• 300405-44-1 3,3'-sulfonyl-bis-benzenesulfonic acid dianilide 
• 1111058-61-7 3,3'-bis(2-phenylprop-2-en-1-ylsulfonyl)diphenyl sulfone 
• 300382-89-2 C₂₆H₂₄N₂O₆S₃ 

Relevant academic research and scientific papers

Synthesis of biologically active of some novel sulphonamides

CONTROLLED chlorosulponation of diphenylsulphone (1), thiaxanthone (2) and benzophenone (3) with chlorosulphonic acid yielded diphenylsulphone-3,3′- disulphonyl-chloride (4a), thiaxanthone-3,3′- disulphonylchloride (5) and benzophenone -3,3′-di

Synthesis of new sulfonyl chlorides on the basis of substituted diphenyl sulfones

-Sulfonation of substituted diphenyl sulfones with excess chlorosulfonic acid at 100°C yields as a rule the corresponding bis-sulfonyl chlorides. The reaction with an equimolar amount of 20% oleum yields products of sulfonation of only one benzene ring.

CHLOROSULFONATION OF SOME DIPHENYL DERIVATIVES

Benzophenone (1), diphenyl sulfone, and 4-nitro-2'-chloro- and 4-nitro-2',6'-dichlorophenyl ethers (23,24) have been chlorosulfonated.The direct yield of benzophenone-3,3'-disulfonyl chloride (2) was low, the majority of product was the disulfonic acid.Diphenyl sulfone (11) with a large amount of chlorosulfonic acid (8 mols) at 140 deg gave the 3,3'-disulfonyl chloride (12).With less reagent (6 mols) at 90 deg a mixture of the 3-sulfonyl chloride (21) and diphenyl sulfone was formed.Subsequent reaction with sodium azide gave the 3-sulfonyl azide (22).The diphenyl ether sulfonyl chlorides (25,26) were very susceptible to hydrolysis, especially (26) which probably accounts for the low yield obtained (31percent).The various sulfonyl chlorides were characterized as amides, azides, hydrazides and hydrazones (Tables I-III) and their i.r., n.m.r., and mass spectral data are included.