73573-57-6Relevant articles and documents
Dihydroxylation of Olefins with Potassium Permanganate Catalyzed by Imidazolium Salt
Khan, Imran,Luo, Zhi-Bin,Valeru, Anil,Xu, Yin,Liu, Bin,Sangepu, Bhavanarushi,Xie, Ji-Min
, p. 1815 - 1819 (2018/02/19)
The development of an efficient and cost-effective cis -dihydroxylation reaction of acrylate derivatives was achieved. The reaction proceeded in acetone with an imidazolium salt as catalyst to furnish the dihydroxylation of olefins at 0-5 °C using KMnO 4 as the oxidant. This efficient and non-aqueous protocol was highly suitable for the large-scale preparation of cis -dihydroxylated compounds from the corresponding acrylate derivatives in high yields without overoxidation.
INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE
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Page/Page column 265; 266, (2017/11/10)
Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
MASKED CARBOXYLATE NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
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Page/Page column 50, (2009/04/24)
Masked carboxylate neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs