73583-44-5

Basic information

• Product Name: 2-Propynoic acid, 3-[4-(phenylmethoxy)phenyl]-
• CAS NO: 73583-44-5
• Molecular Formula: C16H12O3
• Molecular Weight: 252.269
• Mol File: 73583-44-5.mol

Chemical Properties

• CAS DataBase Reference: 2-Propynoic acid, 3-[4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-[4-(phenylmethoxy)phenyl]-(73583-44-5)
• EPA Substance Registry System: 2-Propynoic acid, 3-[4-(phenylmethoxy)phenyl]-(73583-44-5)

Safety Data

• Hazardous Substances Data: 73583-44-5(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 84284-70-8 [4-(benzyloxy)phenyl]acetylene 
• 1030829-56-1 ethyl 3-[4-(benzyloxy)phenyl]prop-2-ynoate 
• 1030828-84-2 3-(4-chlorophenyl)-2-propionic acid ethyl ester 
• 100-39-0 benzyl bromide 
• 705939-74-8 C₁₈H₁₈Br₂O₃ 
• 114943-74-7 methyl 3-(4-benzyloxyphenyl)propiolate 

Downstream Products

• 705934-38-9 5-[4-(benzyloxy)phenyl]-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrazole 
• 1312786-90-5 5-(4-(benzyloxy)phenyl)isothiazol-3-ol 
• 1312786-91-6 5-(4-(benzyloxy)phenyl)isothiazol-3-ol 1-oxide 
• 1312788-39-8 3-(4-(benzyloxy)phenyl)propiolic acid amide 
• 1312788-40-1 5-(4-(benzyloxy)phenyl)-3-(tert-butyldimethylsiloxy)isothiazole 

Relevant articles and documents

Substrate-Assisted, Transition-Metal-Free Diboration of Alkynamides with Mixed Diboron: Regio- and Stereoselective Access to trans-1,2-Vinyldiboronates

A substrate-assisted diboration of alkynamides using the unsymmetrical pinacolato-1,8-diaminonaphthalenato diboron (pinBBdan) is described. The transition-metal-free reaction proceeds in a regio- and stereoselective fashion to exclusively afford trans-vinyldiboronates in good to excellent yields. Notably, Bdan and Bpin are installed on the α- and β-carbon atoms, respectively.

NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE

[Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of solving the problem] A compound of Formula (I): (where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, —NR7—; and R1 to R7 are specific groups), a salt of the compound, or a solvate of the salt or the compound.

Pyrazole derivatives

A compound of the formula (I): wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, etc.; R3 is lower alkoxy, etc.; R4 is hydroxy, etc.; X is O, S, etc.; Y is CH or N; Z is lower alkylene or lower alkenylene; and m is 0 or 1; or salts thereof, which are useful as a medicament.