7361-43-5

Basic information

• Product Name: GLYCYL-L-SERINE
• Synonyms: GLY-SER;GLYCYL-L-SERINE;H-GLY-SER-OH;L-Serine, N-glycyl-;N-(Aminoacetyl)serine;N-glycyl-L-serine;(S)-2-glycylamino-3-hydroxypropionic acid;Gly-L-Ser-OH
• CAS NO: 7361-43-5
• Molecular Formula: C₅H₁₀N₂O₄
• Molecular Weight: 162.14
• EINECS: 230-901-6
• Product Categories: Biochemistry;Oligopeptides;Peptide Synthesis;Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 7361-43-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 201-202℃
• Boiling Point: 513 °C at 760 mmHg
• Flash Point: 264.1 °C
• Appearance: /
• Density: 1.432 g/cm³
• Refractive Index: -9 ° (C=2, H2O)
• Storage Temp.: −20°C
• PKA: pK1:2.98(+1);pK2:8.38(0) (25°C)
• CAS DataBase Reference: GLYCYL-L-SERINE(CAS DataBase Reference)
• NIST Chemistry Reference: GLYCYL-L-SERINE(7361-43-5)
• EPA Substance Registry System: GLYCYL-L-SERINE(7361-43-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 7361-43-5(Hazardous Substances Data)

Usage

Description

GLYCYL-L-SERINE is a dipeptide composed of glycine and L-serine joined by a peptide linkage. It is characterized by its crystalline chemical properties.

Uses

Used in Pharmaceutical Industry:
GLYCYL-L-SERINE is used as a building block for the synthesis of various pharmaceutical compounds due to its dipeptide structure and unique combination of amino acids.
Used in Cosmetics Industry:
GLYCYL-L-SERINE is used as an ingredient in the formulation of cosmetics and personal care products, where it may serve as a moisturizing agent or contribute to the overall efficacy of the product.
Used in Research and Development:
GLYCYL-L-SERINE is used as a research compound for studying the properties and functions of dipeptides in biological systems, as well as for the development of new drugs and therapies.
Used in Nutritional Supplements:
GLYCYL-L-SERINE may be used as an ingredient in nutritional supplements, where it could potentially provide benefits related to muscle growth, recovery, or overall health.
Used in Food Industry:
GLYCYL-L-SERINE could be utilized in the food industry as a flavor enhancer, preservative, or additive, taking advantage of its dipeptide structure and unique properties.

InChI:InChI=1/C5H10N2O4/c6-1-4(9)7-3(2-8)5(10)11/h3,8H,1-2,6H2,(H,7,9)(H,10,11)/t3-/m0/s1

Downstream Products

• 1738-97-2 H-Gly-Ser-OBzl 
• 52661-98-0 cyclo(glycyl-L-seryl) 
• 56-45-1 L-serin 
• 56-40-6 glycine 
• 95767-06-9 N-hippuroyl-L-serine 

Relevant articles and documents

THERAPEUTIC AGENT FOR PRURITUS

The present inventors isolated clone BM095 from a human antibody phage library, which had a strong growth inhibitory activity in the IL-31-dependent Ba/F3 cell growth assay system. When administered to pruritus model mice, the anti-mouse NR10 neutralizing antibody exhibited a marked symptom-suppressing effect. Thus, it was revealed that anti-NR10 neutralizing antibodies are useful as therapeutic agents for pruritus.

Pharmaceutical preparations having diuretic activity

Pharmaceutical preparations having diuretic activity and comprising a peptide of the formula STR1 wherein (a) R1 and R2 are hydrogen and R3 is --OH, or STR2 or Y, or wherein (b) R1 is hydrogen, R2 is CH2 OH or STR3 and R3 is --OH or Y, or wherein (c) R1 is --CH2 OH and R2 is hydrogen or STR4 and R3 is --OH or Y, or wherein (d) R1 is STR5 R2 is hydrogen or --CH2 OH and R3 is --OH, --NHCH2 COOH, or Y, and wherein X is hydrogen, methyl, prolyl, or an N-protective group, and Y is --NH2, --OR4, wherein R4 is linear or branched alkyl or cyclolalkyl having from 1 to 8 carbon atoms, benzyl, phenyl, or STR6