73622-98-7

Usage

General Description

2-(Phenylcarbamoyloxy)propionic acid, also known as fenbufen, is a nonsteroidal anti-inflammatory drug (NSAID) that is mainly used for its analgesic and anti-inflammatory properties. It works by inhibiting the production of prostaglandins, which are responsible for causing pain, inflammation, and fever in the body. Fenbufen is often prescribed to treat conditions such as rheumatoid arthritis, osteoarthritis, and musculoskeletal pain. It is available in both oral and topical formulations and is generally well-tolerated, although it may cause gastrointestinal side effects in some individuals.fenbufen is mainly used for the treatment of arthritis and musculo-skeletal pain and inflammation. It is a non-steroidal anti-inflammatory drug.

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 103-71-9 phenyl isocyanate 
• 62-53-3 aniline 

Downstream Products

• 1012-87-9 5-methyl-3-phenyl-1,3-oxazolidine-2,4-dione 
• 124-38-9 carbon dioxide 
• 106942-22-7 lactanilide 
• 108906-58-7 2-phenylcarbamoyloxy-propionic acid anilide 

Relevant academic research and scientific papers

Method for producing optically active 1-phenylethylamines

PCT No. PCT/EP97/02988 Sec. 371 Date Dec. 17, 1998 Sec. 102(e) Date Dec. 17, 1998 PCT Filed Jun. 9, 1997 PCT Pub. No. WO97/49665 PCT Pub. Date Dec. 31, 1997The invention concerns a new method for producing optically active 1-phenylethylamines, wherein (a) racemic 1-phenylethylamines are reacted with (S)-(-)-N-phenylcarbamate lactic acid in the presence of an aliphatic or aromatic hydrocarbon and in the presence of a lower aliphatic alcohol, wherein the reaction components are measured so that for every mole of racemic amine, between 0.25 and 0.5 mole of (S)-(-)-N-phenylcarbamate lactic acid are present, the reaction mixture is then concentrated at a liquid-phase temperature of up to 40 DEG C., the resulting solid product is separated, treated with diluted, aqueous alkaline lye in the presence of a hydrocarbon, and the respective (R)-amine is isolated by distillation from the organic phase, and if necessary, (b) the mother liquor remaining after the separation of the solid product is reacted in the presence of a lower aliphatic alcohol with (S)-(-)-N-phenylcarbamate lactic acid, wherein the reaction components are measured so that the molar quantity of (S)-(-)-N-phenylcarbamate lactic acid is twice as great as the quantity of (R)-amine still remaining in the mother liquor, the reaction mixture is then concentrated at a liquid-phase temperature of up to 40 DEG C., the resulting solid product is separated and the (S)-amine is isolated by distillation from the mother liquor.