7372-12-5Relevant academic research and scientific papers
A small-molecule chemosensor for the selective detection of 2,4,6-trinitrophenol (TNP)
Pan, Jianting,Tang, Fang,Ding, Aixiang,Kong, Lin,Yang, Longmei,Tao, Xutang,Tian, Yupeng,Yang, Jiaxiang
, p. 191 - 195 (2015/02/05)
A pyridine-based small-molecule receptor (L) for the specific recognition of TNP was synthesised and characterised by 1H NMR, 13C NMR and FT-IR spectra, and the optical properties were studied by UV-Vis absorption and PL spectra. The
Rho-kinase inhibitors
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Page/Page column 13, (2008/06/13)
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., c
Kinetics of reductive N-O bond fragmentation: The role of a conical intersection
Lorance, Edward D.,Kramer, Wolfgang H.,Gould, Ian R.
, p. 15225 - 15238 (2007/10/03)
N-alkoxyheterocycles can act as powerful one-electron acceptors in photochemical electrontransfer reactions. One-electron reduction of these species results in formation of a radical that undergoes N-O bond fragmentation to form an alkoxy radical and a neutral heterocycle. The kinetics of this N-O bond fragmentation reaction have been determined for a series of radicals with varying substituents and extents of delocalization. Rate constants varying over 7 orders of magnitude are obtained. A reaction potential energy surface is described that involves avoidance of a conical intersection. A molecular basis for the variation of the reaction rate constant with radical structure is given in terms of the relationship between the energies of the important molecular orbitals and the reaction potential energy surface. Ab initio and density functional electronic structure calculations provide support for the proposed reaction energy surface.
Synthesis, photophysical, photochemical and electrochemical properties of rhenium(I) diimine complexes with photoisomerizable pyridyl-azo, -ethenyl or -ethyl ligands
Yam, Vivian Wing-Wah,Lau, Victor Chor-Yue,Wu, Li-Xin
, p. 1461 - 1468 (2007/10/03)
A series of rhenium(I) diimine complexes with pyridyl-azo, -ethenyl or -ethyl type ligands, [Re(CO)3(N-N)L]ClO4 and [{Re(CO)3(N-N)}2L′][ClO4]2 {N-N = 2,2′-bipyridine (bpy), 1,10-phenanthroline (phen); L = 4-phenylazopyridine (PHAZO), 4-styrylpyridine (STYPY), [2-(4-pyridyl)ethyl]benzene (PEB), 4-(4-nitrostyryl)pyridine (NSP); L′ = 4,4′-azopyridine (AZO), 1,4-bis[2-(4-pyridyl)ethenyl]benzene (BPENB), 1,4-bis[2-(4-pyridyl)ethyl]benzene (BPEB)} have been synthesized and their photophysical properties studied. The quantum yields for the photoinduced isomerization of the complexes [Re(CO)3(bpy)(NSP)]+ and [Re(CO)3(phen)(NSP)]+ have been determined.
Direct CC Triple Bond Formation from the C=C Double Bond and Direct Hydroxylation into the o-Position of a Nitro Group on the Benzene Nucleus with Potassium t-Butoxide in N,N-DImethylformamide in the Air
Akiyama, Shuzo,Tajima, Kunihiko,Nakatsuji, Shin'ichi,Nakashima, Kenichiro,Abiru, Kazuko,Watanabe, Miwa
, p. 2043 - 2052 (2007/10/03)
A novel and facile method for direct CC acetylenic bond formation from the C=C double bond by treatment with potassium t-butoxide (t-BuOK) in N,N-dimethylformamide in the air has been found in a 9,10-bis(4-substituted styryl)anthracene series, in 4-substituted 4'-nitrostilbene series, and in 1-(p-nitrophenyl)-4-(p-substituted phenyl)-1,3-butadiene series; its scope and limitations have been examined.The ESR spectrum of the reaction against 4-diethylamino-4'-nitrostilbene was measured to identify an anion radical specied expected for explanation of the mechanism of the dehydrogention reaction.Further, cyclic voltammetric measurements of a series of stilbenes and diphenylacetylenes were carried out in connection with the abovw mechanism.In many cases, interestingly, the use of a large excess of t-BuOH brought about succeeding hydroxylation into the ortho-position of a nitro group on the benzene nucleus.The simple hydroxylation is useful for the synthesis of substituted 5-(arylethynyl)-2-nitrophenols, which are expected to function as non-linear optical materials with the corresponding non-hydroxy compounds.The ultraviolet-visible and fluorescence spectral properties were measured and discussed also with those of the related compounds.
Novel Second Harmonic Generation from Intermolecular Charge-transfer Complexes of Styrylpyridinium Tetraphenylborate
Sakaguchi, Hiroshi,Nagamura, Toshihiko,Matsuo, Taku
, p. 209 - 210 (2007/10/02)
Strong second harmonic light was observed for the first time from intermolecular ion-pair charge-transfer complexes of nitrostyrylpyridinium tetraphenylborate, the intensity of which decreased on irradiation at wavelengths longer than 370 nm to induce cha
Heterocyclic ethenyloxanilates as orally active antiallergic agents
Grozinger,Sorcek,Oliver
, p. 487 - 491 (2007/10/02)
Ethyl p-(pyrimidin-4-ylethenyl)oxanilate 2 and many substituted derivatives were found to have oral activity in the PCA assay. The pyrimidine moiety was replaced by other heterocycles but only pyrazine and pyridazine retained activity.
Kinetics of Reaction of Phenacyl Bromide with 3- and 4-Substituted Pyridines and 4-Substituted 4-Styrylpyridines
Shunmugasundaram, A.,Balakumar, S.
, p. 775 - 777 (2007/10/02)
The rates of reaction of phenacyl bromide with 3- and 4-substituted pyridines and 4'-substituted 4-styrylpyridines have been measured in aq. acetone (90percent, v/v) at 30 deg C, 35 deg C and 40 deg C and the activation parameters have been evaluated.Satisfactory Hammett correlations are obtained for both pyridine and styrylpyridine series.The effectiveness of transmission of substituent effect in styrylpyridine system relative to pyridine system in this reaction is calculated to be 0.104.From the Bronsted relationship the coefficient (βN) is found to be 0.48, indicating that the extent of bond formation in the transition state is moderate.
