7372-85-2

Usage

Uses

Used in Organic Synthesis:
2,5-DIMETHYLBIPHENYL is used as a reagent in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows it to participate in a wide range of chemical reactions, making it a versatile building block for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Catalyst Preparation:
2,5-DIMETHYLBIPHENYL is used as a precursor in the preparation of orthopalladated phosphorus ylide complexes and palladium nanoparticles. These catalysts are essential in facilitating various types of chemical reactions, such as the Suzuki coupling reaction, which is a widely used method for the formation of carbon-carbon bonds in organic synthesis. The use of 2,5-DIMETHYLBIPHENYL in the synthesis of these catalysts contributes to the development of more efficient and selective catalytic systems, ultimately leading to the production of high-quality chemical products with reduced environmental impact.

Synthesis Reference(s)

Journal of the American Chemical Society, 92, p. 6088, 1970 DOI: 10.1021/ja00723a061

InChI:InChI=1/C14H14/c1-11-8-9-12(2)14(10-11)13-6-4-3-5-7-13/h3-10H,1-2H3

Upstream product

• 71149-93-4 4’-chloro-2,5-dimethyl-1,1’-biphenyl 
• 69769-82-0 2'-Chloro-2,5-dimethyl-biphenyl 
• 106-42-3 para-xylene 
• 71-43-2 benzene 
• 553-94-6 4-bromo-m-xylene 
• 224311-51-7 johnphos 
• 98-80-6 phenylboronic acid 
• 66003-76-7 Diphenyliodonium triflate 
• 86949-86-2 3-chloro-2',5’-dimethylbiphenyl 

Downstream Products

• 88787-15-9 4-phenyl-<2.2>paracyclophane 
• 135078-60-3 5-phenyl-2,11-dithia<3.3>paracyclophane 
• 135078-62-5 6,15-Diphenyl-3,10-dithia-tricyclo[10.2.2.2^5,8]octadeca-1⁽¹⁵⁾,5⁽¹⁸⁾,6,8⁽¹⁷⁾,12⁽¹⁶⁾,13-hexaene 
• 92151-76-3 Fluorene-3-carboxylic acid 
• 72570-98-0 2-Amino-7-nitro-fluoren 
• 92254-03-0 5-methyl-[1,1'-biphenyl]-2-carboxylic acid 
• 401573-78-2 2-methyl-5-biphenylcarboxylic acid 
• 4445-51-6 2,5-biphenyldicarboxylic acid 

Relevant academic research and scientific papers

Palladium-catalyzed arylation of simple arenes with iodonium salts

The development of an arylation protocol for simple arenes with diaryliodonium salts using the Herrmann-Beller palladacycle catalyst is reported. The reaction takes simple aromatic feedstocks and creates valuable biaryls for use in all sectors of the chem

Ligands for metals and improved metal-catalyzed processes based thereon

One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.

Ligands for metals and improved metal-catalyzed processes based thereon

One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.

Aromatic hydrocarbons in the gaseous and condensed phase. A nuclear decay study

A nuclear technique based on the spontaneous decay of tritiated precursors has been used in a comparative stydy of aromatic phenylation by free phenylinium ions, both in the gas and liquid phase.The mechanism of the major competitive processes promoted by phenylinium ion attack, are discussed.

Photolysis of Some ortho-Methylated Monochlorobiphenyls

A series of monochloro-o-methylated biphenyls was photolysed.Quantum yields of dechlorination lie in between the low values observed for 3- and 4-chlorobiphenyl and the high values obtained for 2-chlorobiphenyl.The results are interpreted in terms of raising the energy of the excited state due to steric crowding of the ortho-substituent and relief of strain upon the departure of an ortho-chlorine.