7373-13-9

Basic information

• Product Name: 2-OCTADECANONE
• Synonyms: Methyln-hexadecylketone;HEXADECYL METHYL KETONE;2-OCTADECANONE
• CAS NO: 7373-13-9
• Molecular Formula: C₁₈H₃₆O
• Molecular Weight: 268.48
• Product Categories: Building Blocks;C15 to C38;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
• Mol File: 7373-13-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 50-54℃
• Boiling Point: 145℃/0.7mmHg(lit.)
• Flash Point: 77.6 °C
• Appearance: /
• Density: 0.8453 (estimate)
• Vapor Pressure: 0.000287mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• CAS DataBase Reference: 2-OCTADECANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-OCTADECANONE(7373-13-9)
• EPA Substance Registry System: 2-OCTADECANONE(7373-13-9)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 7373-13-9(Hazardous Substances Data)

Usage

General Description

2-Octadecanone, also known as stearketone, is a long-chain ketone with the chemical formula C18H36O. It is a colorless to pale yellow liquid with a waxy odor and is found naturally in the wax of certain plants. 2-Octadecanone is commonly used in the production of perfumes and fragrances due to its pleasant aroma and is also used as a flavoring agent in the food industry. Additionally, it is used as a raw material in the production of cosmetics, detergents, and other personal care products. In the pharmaceutical industry, 2-Octadecanone is used as an intermediate in the synthesis of various medications and as an important building block in organic chemistry.

InChI:InChI=1/C18H36O/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(2)19/h3-17H2,1-2H3

Upstream product

• 629-72-1 pentadecyl bromide 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 506-12-7 heptadecanoic acid 
• 543-80-6 barium(II) acetate 
• 57661-22-0 1-methanesulfinyl-octadecan-2-one 
• 7390-81-0 2-hexadecyloxirane 
• 4111-54-0 lithium diisopropyl amide 
• 593-32-8 octadecan-2-ol 
• 105679-03-6 1-Tellanyl-octadecan-2-ol 
• 112-80-1 cis-Octadecenoic acid 
• 112-88-9 octadec-1-ene 
• 1731-92-6 methyl margarate 
• 392686-83-8 Phenethyl-prop-(E)-ylidene-amine 
• 852152-06-8 (2Z,4E)-3-hydroxy-6-oxodocosa-2,4-dienoic acid methyl ester 

Downstream Products

• 65351-35-1 eicosane-2,4-dione 
• 110876-17-0 3-hydroxy-3-methyl-nonadecanoic acid 
• 102885-92-7 3-hydroxy-3-methyl-nonadecanoic acid ethyl ester 
• 103045-14-3 (+/-)-benzyl-(1-methyl-heptadecyl)-amine 
• 103045-14-3 benzyl-((S)-1-methyl-heptadecyl)-amine 
• 103045-14-3 benzyl-((R)-1-methyl-heptadecyl)-amine 
• 16538-04-8 (+/-)-N-(1-methyl-heptadecyl)-acetamide 
• 26547-18-2 (+/-)-2-amino-octadecane 
• 64-19-7 acetic acid 
• 57-10-3 1-hexadecylcarboxylic acid 
• 102013-92-3 octadecan-2-one semicarbazone 
• 593-32-8 octadecan-2-ol 
• 59934-70-2 3-methyl-nonadec-1-yn-3-ol 
• 94377-04-5 octadecan-2-one oxime 

Relevant articles and documents

Iron-Catalyzed Wacker-type Oxidation of Olefins at Room Temperature with 1,3-Diketones or Neocuproine as Ligands**

Herein, we describe a convenient and general method for the oxidation of olefins to ketones using either tris(dibenzoylmethanato)iron(III) [Fe(dbm)3] or a combination of iron(II) chloride and neocuproine (2,9-dimethyl-1,10-phenanthroline) as catalysts and phenylsilane (PhSiH3) as additive. All reactions proceed efficiently at room temperature using air as sole oxidant. This transformation has been applied to a variety of substrates, is operationally simple, proceeds under mild reaction conditions, and shows a high functional-group tolerance. The ketones are formed smoothly in up to 97 % yield and with 100 % regioselectivity, while the corresponding alcohols were observed as by-products. Labeling experiments showed that an incorporated hydrogen atom originates from the phenylsilane. The oxygen atom of the ketone as well as of the alcohol derives from the ambient atmosphere.

Conversion of Olefins into Ketones by an Iron-Catalyzed Wacker-type Oxidation Using Oxygen as the Sole Oxidant

We describe a mild and operationally simple procedure for the oxidation of olefins into ketones. The reaction is catalyzed by the hexadecafluorinated iron–phthalocyanine complex FePcF16 with stoichiometric amounts of triethylsilane as an additive under oxygen atmosphere to give ketones in good to high yields with excellent chemoselectivity and functional group tolerance. Ketone formation proceeds in up to 95 % yield and with 100 % regioselectivity while the corresponding alcohols were observed as side products.

Phenanthroline decorated by a crown ether as a module for metallorganic polyoxometalate hybrid catalysts: The wacker type oxidation of alkenes with nitrous oxide as terminat oxidant

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