73746-72-2

Upstream product

• 73746-69-7 (4S,5S)-2-<4-<(Trimethylsilyl)oxy>butyl>-4-(methoxymethyl)-5-phenyl-2-oxazoline 
• 106-95-6 allyl bromide 
• 73713-17-4 (4S,5S)-2-n-Pentyl-4-(methoxymethyl)-5-phenyl-2-oxazoline 
• 52075-14-6 (4S,5S)-(-)-4,5-dihydro-4-methoxymethyl-2-methyl-5-phenyloxazole 
• 2427-16-9 5-hydroxy-pentanenitrile 
• 34714-04-0 1-trimethylsiloxy-3-bromo-propane 
• 73746-66-4 (4S,5S)-2-But-3-enyl-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 73746-82-4 4-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-butan-1-ol 
• 55232-20-7 (4S,5S)-2-<3-<(Trimethylsilyl)oxy>propyl>-4-(methoxymethyl)-5-phenyl-2-oxazoline 
• 73746-59-5 (4S,5S)-4-Methoxymethyl-2-(1-methyl-3-trimethylsilanyloxy-propyl)-5-phenyl-4,5-dihydro-oxazole 
• 73746-60-8 (4S,5S)-2-(1-Ethyl-3-trimethylsilanyloxy-propyl)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 73746-61-9 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(2-trimethylsilanyloxy-ethyl)-butyl]-4,5-dihydro-oxazole 
• 73746-63-1 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(2-trimethylsilanyloxy-ethyl)-pentyl]-4,5-dihydro-oxazole 

Relevant academic research and scientific papers

Asymmetric Synthesis of 2-Substituted Butyrolactones and Valerolactones

The use of chiral oxazolines 1, 2, 5, and 8 under asymmetrically induced alkylation conditions gave α-substituted oxazolines 3, 6, 9, and 13 which were hydrolyzed to α-substituted butyro- and valerolactones 4 and 11.Either enantiomer of the lactones could be prepared in predictable absolute configuration by reversing the order of alkyl group introduction.The lactones were prepared in 60-86 percent enantiomeric excess which was determined by either chemical correlation or high-pressure liquid chromatography of the diastereomers 10.