55232-20-7

Upstream product

• 75-21-8 oxirane 
• 75-77-4 chloro-trimethyl-silane 
• 52075-14-6 (4S,5S)-(-)-4,5-dihydro-4-methoxymethyl-2-methyl-5-phenyloxazole 

Downstream Products

• 73746-63-1 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(2-trimethylsilanyloxy-ethyl)-pentyl]-4,5-dihydro-oxazole 
• 73746-59-5 (4S,5S)-4-Methoxymethyl-2-(1-methyl-3-trimethylsilanyloxy-propyl)-5-phenyl-4,5-dihydro-oxazole 
• 73746-73-3 (4S,5S)-2-(1-Benzyl-4-trimethylsilanyloxy-butyl)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 73746-77-7 4-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-5-phenyl-pentan-1-ol 
• 73746-72-2 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(3-trimethylsilanyloxy-propyl)-but-3-enyl]-4,5-dihydro-oxazole 
• 73746-71-1 (4S,5S)-4-Methoxymethyl-5-phenyl-2-(1-propyl-4-trimethylsilanyloxy-butyl)-4,5-dihydro-oxazole 
• 73746-70-0 (4S,5S)-2-(1-Ethyl-4-trimethylsilanyloxy-butyl)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 73758-09-5 (4S,5S)-4-Methoxymethyl-2-(1-methyl-4-trimethylsilanyloxy-butyl)-5-phenyl-4,5-dihydro-oxazole 
• 51594-34-4 (1S,2S)-2-amino-3-methoxy-1-phenyl-1-propanol 
• 73746-62-0 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(2-trimethylsilanyloxy-ethyl)-but-3-enyl]-4,5-dihydro-oxazole 
• 73746-61-9 (4S,5S)-4-Methoxymethyl-5-phenyl-2-[1-(2-trimethylsilanyloxy-ethyl)-butyl]-4,5-dihydro-oxazole 
• 73746-60-8 (4S,5S)-2-(1-Ethyl-3-trimethylsilanyloxy-propyl)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 

Relevant academic research and scientific papers

Asymmetric Synthesis of 2-Substituted Butyrolactones and Valerolactones

The use of chiral oxazolines 1, 2, 5, and 8 under asymmetrically induced alkylation conditions gave α-substituted oxazolines 3, 6, 9, and 13 which were hydrolyzed to α-substituted butyro- and valerolactones 4 and 11.Either enantiomer of the lactones could be prepared in predictable absolute configuration by reversing the order of alkyl group introduction.The lactones were prepared in 60-86 percent enantiomeric excess which was determined by either chemical correlation or high-pressure liquid chromatography of the diastereomers 10.