737796-32-6Relevant academic research and scientific papers
Photoassisted access to complex polyheterocycles containing a β-lactam moiety
Umstead, Weston J.,Mukhina, Olga A.,Kutateladze, Andrei G.
, p. 182 - 188 (2016)
Intramolecular cycloadditions of aza-o-xylylenes generated via excited state intramolecular proton transfer (ESIPT) to furanacetic acid-based unsaturated pendants was shown to overcome the unfavorable energetics of the azetidinone ring formation, offering rapid access to β-lactams as primary photoproducts. These 2,3- and 3,4-dihydrofuran-containing reactive intermediates are suitable for a broad spectrum of postphotochemical transformations yielding complex polyheterocyclic molecular architectures possessing the β-lactam moiety.
Room temperature silylation of alcohols catalyzed by metal organic frameworks
Dhakshinamoorthy, Amarajothi,Santiago-Portillo, Andrea,Concepción, Patricia,Herance, José R.,Navalón, Sergio,Alvaro, Mercedes,Garcia, Hermenegildo
, p. 2445 - 2449 (2017/07/24)
The commercial Al(OH)(BDC) (BDC: 1,4-benzenedicarboxylic acid) metal organic framework (Basolite A100) is a suitable heterogeneous catalyst for the silylation of benzylic and aliphatic alcohols by hexamethyldisilazane in toluene at room temperature. Al(OH
Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate: An efficient heterogeneous catalyst for silylation of alcohols and phenols with HMDS
Lee, Sang-Hyeup,Kadam, Santosh T.
experimental part, p. 608 - 615 (2011/11/12)
Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate (30P/S-Bi) effectively activates hexamethyldisilazane (HMDS) for the silylation of alcohols and phenols. By the use of this heterogeneous catalytic system, a wide range of alcohols as well as phenols are converted into their corresponding trimethylsilyl ethers in high yield under mild reaction conditions. The catalyst was reused more than 10 times without significant loss of its catalytic activity.
Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed BY poly(4-VINYLPYRIDINIUM TRIBROMIDE)
Ghorbani-Choghamarani, Arash,Zolfigol, Mohammad Ali,Hajjami, Maryam,Darvishi, Khorshid,Gholamnia, Laleh
experimental part, p. 607 - 615 (2011/08/05)
A very efficient procedure for the protection of alcohols and phenols is presented. The mixture of 1,1,1,3,3,3-hexamethyldisilazane (HMDS) and catalytic amounts of poly(4-vinylpyridinium tribromide) was found to be effective for the trimethylsilylation of
Discovery, synthesis, and structure-activity studies of tetrazole based growth hormone secretagogues
Hernandez, Andres S.,Cheng, Peter T.W.,Musial, Christa M.,Swartz, Stephen G.,George, Rocco J.,Grover, Gary,Slusarchyk, Dorothy,Seethala, R. Krishna,Smith, Mark,Dickinson, Kenneth,Giupponi, Leah,Longhi, Daniel A.,Flynn, Neil,Murphy, Brian J.,Gordon, David A.,Biller, Scott A.,Robl, Jeffrey A.,Tino, Joseph A.
, p. 5928 - 5933 (2008/04/03)
A novel class of Growth Hormone Secretagogues (GHS), based on a tetrazole template, has been discovered. In vitro SAR and in vivo potency within this new class of GHS are described. The tetrazole 9q exhibits good oral bioavailability in rats and dogs as w
