7383-87-1Relevant academic research and scientific papers
Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes
Gao, Pin,Chen, Liang-An,Brown, M. Kevin
supporting information, p. 10653 - 10657 (2018/09/10)
A three-component coupling of aryl bromides, arylboron reagents, and alkenylarenes is presented. The method tolerates a variety of substitution patterns on all of the components. In particular, 1,2-disubstituted alkenylarenes are suitable and undergo highly diastereoselective diarylation.
Iridium-promoted, palladium-catalyzed direct arylation of unactivated arenes
Durak, Landon J.,Lewis, Jared C.
supporting information, p. 620 - 623 (2014/03/21)
A Pd-catalyzed cross-coupling reaction between Cp*(PMe 3)IrBn2 and aryl halides was developed. Examining the scope of this reaction led to the discovery that Cp*(PMe 3)IrMeCl activates C-H bonds on arene substrates that undergo subsequent Pd-catalyzed cross-coupling with aryl iodides. This Ir-promoted, Pd-catalyzed direct arylation is notable for its distal selectivity on substituted arenes lacking directing groups or a particular electronic bias.
C-H arylation of unactivated arenes with aryl halides catalyzed by cobalt porphyrin
To, Ching Tat,Chan, Tek Long,Li, Bao Zhu,Hui, Ying Ying,Kwok, Tsz Yiu,Lam, Suet Yu,Chan, Kin Shing
supporting information; experimental part, p. 1023 - 1026 (2011/03/20)
A general procedure for cobalt-catalyzed direct C-H arylation of unactivated arenes has been discovered. This method employs aryl halides as the direct coupling partners with arenes without using any Grignard-type reagents. This catalysis opens a new methodology for the preparation of symmetrical as well as unsymmetrical biaryls in a user-friendly approach.
PREPARATION OF SOME TRIMETHYL- AND METHYLETHYLBIPHENYLS AND REACTIVITY OF AROMATIC HYDROCARBONS IN THE GOMBERG REACTION
Novrocik, Jan,Novrocikova, Marta,Titz, Milos
, p. 3140 - 3149 (2007/10/02)
Trimethyl- and methylethylbiphenyls with the alkyl groups in the both phenyl rings have been prepared by the Gomberg reaction and identified by the capillary gas-liquid chromatography.Depending on choice of the aromatic hydrocarbon either individual isomers or their mixtures (three at the most) have been obtained which were contaminated with compounds of diarylmethane type in many cases.The methylethylbiphenyls have only been prepared as mixtures contaminated with diarylmethanes.These side products have been prepared by independent syntheses.A method has been developed for isolation and separation of mixtures of trimethyl- and methylethylbiphenyls from the reaction products containing tarry products.The method is suitable for preparation of small amounts of some analytical standards.The HMO method has been used for calculation of values of the radical superdelocalizabilities at individual centres in the molecules of o-, m- and p-xylene, toluene and ethylbenzene, and these values have been compared with composition of the Gomberg reaction products from these hydrocarbons.The competitive technique has been used for comparison of the reactivities of the mentioned aromatic substrates in the Gomberg reactions.
