73870-26-5Relevant academic research and scientific papers
Phosphonium Ylide-Mediated Programmable Fluorination to Access Mono- And Difluoromethylarenes
Zheng, Yu,Xie, Zhen-Zhen,He, Xian-Chen,Chen, Yan-Shan,Cheng, Wen-Shuo,Chen, Kai,Xiang, Hao-Yue,Chen, Xiao-Qing,Yang, Hua
supporting information, p. 2538 - 2542 (2021/04/13)
Compounds bearing fluorinated moieties are pervasive in a wide range of pharmaceuticals and agrochemicals. The installation of fluorinated units is a persistently vital task in synthetic chemistry, where facile and manipulable assays are highly demanding.
CYCLOPENTYLBENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PSYCHOTIC AND COGNITIVE DISORDERS
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, (2015/05/05)
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein n, L, X, Ra, Rb, R1, R2 and R3 their preparation, pharmaceutical compositions containing them and their use in therapy.
SUBSITUTED CYCLOPENTANES, TETRAHYDROFURANES AND PYRROLIDINES AS OREXIN RECEPTOR ANTAGONISTS
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, (2015/09/28)
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, Formula (I) wherein L,X, Ra, Rb, R 1, R2 and R3 are as defined in the specification, processes fo
Efficient synthesis of cis-2,6-di-(2-quinolylpiperidine)
Ding, Derong,Dwoskin, Linda P.,Crooks, Peter A.
, p. 5211 - 5213 (2013/09/02)
An efficient synthesis of cis-2,6-di-(2-quinolylpiperidine) has been developed. The key steps involve Wittig reaction of N-Cbz-protected cis-piperidine-2,6-dicarboxaldehyde (3) with 2-(triphenylphosphinyl-methyl) quinoline bromide (4) and sequential removal of the N-Cbz group and double bond reduction. This synthetic procedure provides an efficient preparation for this useful norlobelane analogue.
HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF
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Page/Page column 135, (2011/12/14)
Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes
