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Upstream product

• 98875-33-3 bis(triphenylphosphine)gold(I) nitrate 
• 26042-63-7 silver(I) hexafluorophosphate 
• 14243-64-2 (triphenylphosphine)gold(I) chloride 
• 60969-19-9 thallium(I) hexafluorophosphate 
• 754194-75-7 [(gold(I))(6-CH2CMe3-2,2'-bipyridine)(η2-styrene)][PF6] 
• 603-35-0 triphenylphosphine 
• 17084-13-8 potassium hexafluorophosphate 
• 39929-21-0 (tetrahydrothiophene)gold(I) chloride 

Relevant academic research and scientific papers

Covalently bonded bis(phosphane)gold(I) cations in a cross-linked phosphazene polymeric matrix as recyclable supported catalysts for thermal and microwave-assisted hydration of alkynes

The unexpected finding that the complex [Au(PPh3) 2]PF6 (C1) catalyses the specific hydration of 1-octyne, (p-phenoxyphenyl) acetylene, phenylacetylene, (p-chlorophenyl)-acetylene and benzylacetylene at 100°C in the presence of H2SO4 and THF or methanol as solvents, specially using microwave radiation, led to the first gold(I) recyclable catalysts for this reaction. The phosphazene polymeric framework of idealised formula {[NP(O2C12H 8)]0.85[NP(OC6H4PPh 2)2 (AuPF6)0.5]0.15} n (C2), and the newly synthesised cyclomatrix material of idealised formula {[N3P3(OC6H4PPh 2)6]-(AuPF6)3.5}n (C3), both having cationic [-Ph2P-Au+-PPh2-] cross-linking sites, catalysed the complete hydration of terminal alkynes at 100°C and 150°C and could be used six and four times respectively without significant loss of activity. The mechanism of the catalytic system is based on the initial reversible displacement of one anchoring O-C 6H5-PPh2 group from the [-Ph 2P-Au+-PPh2-] cross-linking sites by an alkyne molecule. Using microwave radiation, the hydration of (p-phenoxyphenyl) acetylene, phenylacetylene, (p-chlorophenyl)acetylene and benzylacetylene can be completed in 5 min to 2 h in the absence of any gold(I) catalyst.

Synthesis, characterization, and reactivity of cationic gold(I) α-diimine complexes

A series of cationic gold(I) α-diimine complexes of the type [(NHC)Au(α-diimine)]X or [(PPh3)Au(α-diimine)]X, where NHC = IPr, α-diimine = BIAN-dipp, X = PF6 (1); X = BF 4 (2); X = SbF6 (3); NHC = ItBu, α-diimine = BIAN-dipp, X = PF6 (4); X = BF4 (5); NHC = IMes, α-diimine = BIAN-dipp, X = PF6 (6); PPh3, α-diimine = BIAN-dipp, X = PF6 (7); NHC = IPr, α-diimine = DAB-Mes, X = PF6 (8, 10) bearing an N-heterocyclic carbene (NHC) or a phosphine ligand, have been synthesized and characterized by NMR spectroscopy and single crystal X-ray diffraction. The stability of the new complexes and their catalytic activity for the intermolecular addition of the indole nucleophilic carbon to 1,6-enyne were also investigated.

Synthesis of gold(I) phosphine complexes containing the 2-BrC6F4PPh2 ligand: Evaluation of anticancer activity in 2D and 3D spheroidal models of HeLa cancer cells

Newly synthesised mononuclear gold complexes containing the 2-BrC6F4PPh2 ligand have been fully characterised and their anticancer activity towards five human tumor [prostate (PC3), glioblastoma (U87MG), cervical (HeLa), fibrosarcoma (HT1080), ovarian (SKOV-3)] and normal human embryonic kidney (Hek-293T) cell lines investigated. Some of the synthesised gold complexes displayed higher cytotoxicity than cisplatin towards PC-3, HeLa and U87MG cells and inhibited the thioredoxin reductase (TrxR) enzyme, which is considered a potential target for new compounds in cancer treatment. The more physiologically relevant tumor spheroid assay demonstrated the superior potency of these gold phosphine complexes in inhibiting the growth of cervical carcinoma cell line HeLa (3D) spheroidal models. The mechanism of cell death was shown to be apoptotic cell death through cell cycle arrest, mitochondrial membrane depolarisation and increased ROS production.

Designed synthesis of metal-organic frameworks containing gold(I) cations supported in phosphazene-phosphine polymeric matrices

The reaction of the polyphosphazenes {[NP(O2C12H8)]1-x [NP(OC6H4PPh2)2]x }n, x = 0.15 (1a), 0.25 (1b), 0.35 (1c), with [Au(THT)Cl] (THT = tetrahy

Reaction of gold(III) oxo complexes with alkenes. Synthesis of unprecedented gold alkene complexes, [Au(N,N)(alkene)][PF6]. Crystal structure of [Au(bipyip)(η2-CH2=CHPh)] [PF6] (bipyip = 6-

Gold alkene complexes [Au(bipyR)(η2-alkene)] [PF6] (bipyR = 6-alkyl-2,2′-bipyridine) have been obtained by reaction of gold(III) oxo complexes [Au2(bipy R)2(μ-O)2][PF

Synthesis, structure, and reactivity of Pt3Au and Pt3Au2 cluster complexes

The complex [Pt3(μ3-H)(μ-dppm)3]+ (dppm = Ph2PCH2PPh2) reacts with LAu+ (L = PPh3) to give [Pt3(μ3-H)(μ3-AuL)(μ-dppm)

X-ray crystal structure and31P NMR solution studies of [Ir2(dimen)4(PPh3)Au(PPh3)](PF 6)3 (dimen = 1,8-diisocyano-p-menthane). Observation of partial site preference in the formation of "outside" Ag and Au adducts

The reaction of [M(PPh3)2](PF6) (M = Ag, Au) with [Ir2(dimen)4](PF6)2 leads to the formation of heteronuclear complexes of the general formula [Ir2(dimen)4(PPh3)M(PPh3)](PF 6)3. Recrystallization of the Au complex from CH3CN/ether solution afforded crystals of [Ir2(dimen)4(PPh3)Au(PPh3)](PF 6)3-CH3CN (AuIr2C86H105F18N9P 5) that were the subject of an X-ray crystal structure characterization. The complex crystallizes in the monoclinic space group Cc (No. 9) with Z = 4; a = 24.79 (2), b = 15.792 (6), c = 23.307 (6) ?; β = 94.15 (4)°; V = 9102 A°3. At convergence, R = 0.055 and Rw = 0.064 for 6382 observed reflections. The crystal contains tripositive cations with a Au(PPh3)+ unit occupying one of the [Ir2(dimen)4]2+ axial sites and a PPh3 in the second axial position. The PPH3-Ir2-Au(PPh3) moiety features a two-electron two-center Ir-Au bond with a Ir-Au distance of 2.607 (2) ?. Au-P and Ir-P bond distances in the structure are 2.199 (7) and 2.482 (7) ?, respectively. The Ir(CNR)4 planes are nearly staggered with a twist angle of 39°. The Ir-Ir separation is 2.986 (2) ?. From 31P{1H} NMR solution studies and homonuclear 31P{1H} δ/J-resolved NMR spectroscopy, a nonstatistical distribution of five out of six different geometric isomers is present in CH2Cl2 solutions of both the Ag+ and Au+ complexes.

Chemistry of Di- and Tri-metal Complexes with Bridging Carbene or Carbyne Ligands. Part 31. Synthesis and Crystal Structures of the Compounds *CH2Cl2 and 3-CR)(CO)2(PMe3)3(η-C5H5)> (R =C6H4Me-4)

Treatment of a mixture of the salts and TlPF6 in tetrahydrofuran (thf) with affords the bridged p-tolylmethylidene complex , the structure of which has been established by a single-crystal X-ray diffraction study.As expected, the Au-W bond is spanned by the CH(C6H4Me-4) group.The μ-C-W separation is relatively short whereas the μ-C-Au distance is relatively long .To account for these features a three-centre two-electron μ-C-Au-W interaction is postulated.Addition of (1+) fragments, generated in situ from and TlPF6 in dichloromethane, to the alkylidynetungsten compounds CR)(CO)2(η-C5H5)> (R= C6H4Me-4 or Me) affords the salts .N.m.r. studies (1H, 31P-(1H), and 13C-(1H)) on solutions of these salts, however, reveal that the cations dissociate, affording equilibrium mixtures containing the species CR)(CO)2(η-C5H5))2>(1+) and (1+).The trimetal compound 3-CR)(CO)2(PMe3)3(η-C5H5)> (R= C6H4Me-4) has been prepared by two routes: from the reaction between CR)(CO)2(η-C5H5)2> and , and by addition of to .The structure of 3-CR)(CO)2(PMe3)3(η-C5H5)> has been established by X-ray crystallography.A triangular array of metal atoms is asymmetrically bridged by the CR ligand 3-C-Au 2.21(4), μ3-C-Pt 1.97(4), and μ3-C-W 2.01(4) Angstroem>.The Au-Pt separation suggests that there is little or no direct metal-metal bonding between these two metal atoms.The tungsten atom carries the cyclopentadienyl ligand and two CO groups, but the latter are appreciably non-linear.The gold and platinum atoms are ligated by one and two PMe3 groups, respectively.

CHEMISTRY OF DI- AND TRI-METAL COMPLEXES WITH BRIDGING CARBENE OR CARBYNE LIGANDS. PART 28. SYNTHESIS AND X-RAY CRYSTAL STRUCTURES OF THE COMPOUNDS AND (R=C6H4Me-4)

The compound CR)(CO)2(η-C5H5)> (R=C6H4Me-4) reacts readily with the complexes (M =Mo or W) in hexane at reflux to afford the trimetal compounds 2-CO)2(CO)4(η-C5H5)2>, n.m.r. and i.r. data for which are reported.The molybdenum-ditungsten compound was fully characterised structurally by a single-crystal X-ray difraction study.It comprises a bent W-Mo-W spine with the Mo-W bonds bridged by CC6H4Me-4 groups.The Mo atom carries two terminal carbonyl ligands; the bisector of the angle between these is an approximate axis of two-fold symmetry for the molecule as a whole.The two molybdenum-tungsten-carbene ring systems are not coplanar, but are twisted relative to one another so that the two planes are nearly orthogonal.The Mo-W and Mo-C(carbene) bonds to not form a pseudo-tetrahedral group, however, because of the presence of two cis carbonyl ligands on the central Mo atom.An especially interesting feature is that, of the two terminal carbonyl ligands on each tungsten atom, one is η2-bonded to the central molybdenum atom.The significance of this is discussed.Crystals are triclinic, space group P1 (no. 2), and the structure has been refined to R = 0.038 for 3 711 intensities measured to 2θ = 55 deg at 210 K.Treatment of chloro(tetrahydrothiophene)gold(I) with CR)(CO)2(η-C5H5)> in tetrahydrofuran in the presence of TlPF6 affords the salt , while and CR)(CO)2(η-C5H5)> give .The spectroscopic data (i.r. and n.m.r.) for these gold and silver compounds are discussed, and the structure of the former has been established by X-ray diffraction.The cation has a bent W-Au-W spine with the Au-W bonds bridged by the CC6H4Me-4 groups.The dihedral angle between the two dimetallacyclopropene rings is 62 deg.The tungsten atoms carry η-C5H5 groups and two terminally bound CO ligands.Crystals are orthorhombic, space group Pnna (no. 52), and the structure has been refined to R = 0.050 for 1 654 reflections measured to 2θ = 50 deg at 200 K.