73873-61-7

Basic information

• Product Name: (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid
• Synonyms: (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid;trans-4-methoxycyclohexane-1-carboxylic acid;trans-4-Methoxycyclohexanecarboxylic acid
• CAS NO: 73873-61-7
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.19496
• Mol File: 73873-61-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid(73873-61-7)
• EPA Substance Registry System: (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid(73873-61-7)

Safety Data

• Hazardous Substances Data: 73873-61-7(Hazardous Substances Data)

Usage

Uses

trans-4-Methoxycyclohexanecarboxylic Acid is used as a reactant in the preparation of pyrazolylmethylamino isoindoline diones as cereblon binders for degradation of Ikaros useful in treatment of diseases.

Upstream product

• 100-09-4 4-methoxybenzoic acid 
• 121-98-2 methyl 4-methoxybenzoate 
• 137058-17-4 Methyl cis/trans-4-methoxycyclohexanecarboxylate 

Downstream Products

• 178609-55-7 3-(4-methoxy-cyclohexyl)-3-oxo-propionic acid ethyl ester 
• 120552-57-0 (1r,4r)-4-methoxycyclohexane-1-carbaldehyde 
• 101869-74-3 ((1R,4R)-4-methoxycyclohexyl)methanol 

Relevant articles and documents

Electrocatalytic hydrogenation of benzoic acids in a proton-exchange membrane reactor

The highly efficient chemoselective electrocatalytic hydrogenation of benzoic acids (BAs) to cyclohexanecarboxylic acids (CCAs) was carried out in a proton-exchange membrane reactor under mild conditions without hydrogenation of the carboxyl group. Among the investigated catalysts, the PtRu alloy catalyst was found to be the most suitable for achieving high current efficiencies for production of CCAs. An electrochemical spillover mechanism on the PtRu alloy catalyst was also proposed.