120552-57-0

Usage

Uses

Used in Organic Synthesis:
Cyclohexanecarboxaldehyde, 4-methoxy(9CI) is used as an intermediate in organic synthesis for the production of various industrial chemicals. Its reactivity and chemical structure make it a useful building block in the synthesis of complex organic molecules.
Used in Fragrance Industry:
Due to its distinctive odor, Cyclohexanecarboxaldehyde, 4-methoxy(9CI) is used as a fragrance ingredient in perfumes and cosmetic products. It contributes to the creation of unique and appealing scents in these consumer goods.
Used in Pharmaceutical Industry:
Cyclohexanecarboxaldehyde, 4-methoxy(9CI) has potential applications in the pharmaceutical industry. Its versatile chemical structure allows for the development of new drug candidates and active pharmaceutical ingredients.
Used in Agrochemical Industry:
Cyclohexanecarboxaldehyde, 4-methoxy(9CI) also has potential uses in agrochemicals, where its reactivity and chemical properties can be harnessed for the development of new pesticides, herbicides, or other agricultural chemicals.

Upstream product

• 101869-74-3 (4-methoxy-cyclohexyl)-methanol 
• 73873-60-6 cis-methyl 4-methoxycyclohexane-1-carboxylate 
• 101869-74-3 ((1R,4R)-4-methoxycyclohexyl)methanol 
• 3618-04-0 trans-4-hydroxy-cyclohexane carboxylic acid ethyl ester 
• 13482-23-0 4-methoxycyclohexanone 
• 223677-02-9 ethyl 4-methoxycyclohexanecarboxylate 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 56292-99-0 4-methoxycyclohexanone ethylene ketal 
• 22428-87-1 4,4-ethylenedioxycyclohexan-1-ol 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 

Relevant academic research and scientific papers

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure provides a compound of Formula (I′): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.

3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure provides a compound of Formula (I′): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein R1, R2, Rx, X1, n, n1, and q are as defined herein, and methods of making and using same.

ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy

Different inflammatory diseases and allergic reactions are mediated by leukotrienes, which arise from the oxygenation of arachidonic acid catalyzed by 5-lipoxygenase (5-LO). One promising approach for an effective anti-leukotriene therapy is the inhibition of this key enzyme. This study presents the synthesis and development of a potent and direct 5-LO inhibitor based on the well characterized 5-benzylidene-2-phenylthiazolone C06, whose further pharmacological investigation was precluded due to its low solubility. Through optimization of C06, evaluation of structure-activity relationships including profound assessment of the thiazolone core and consideration of the solubility, the 5-benzyl-2-phenyl-4-hydroxythiazoles represented by 46 (ST-1829, 5-(4-chlorobenzyl)-2-p-tolylthiazol-4-ol) were developed. Compound 46 showed an improved 5-LO inhibitory activity in cell-based (ICinf50/inf values 0.141/4M) and cell-free assays (ICinf50/inf values 0.03 1/4M) as well as a prominent enhanced solubility. Furthermore, it kept its promising inhibitory potency in the presence of blood serum, excluding excessive binding to serum proteins. These facts combined with the non-cytotoxic profile mark a major step towards an effective anti-inflammatory therapy.

HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES

Compounds of formula (I) are suitable for use as herbicides: wherein R is methyl, ethyl, vinyl, ethynyl or cyclopropyl, R1 is hydrogen, C1-C6alkyl, C1-C6haloalkyl, C3-C7cycloalkyl, C1-C6alkoxy, C1-C6haloalkoxy, vinyl, propenyl, ethynyl, propynyl, halogen, or optionally substituted phenyl, R2 is methyl, ethyl, vinyl, ethynyl or methoxy, R3 and R4 are hydrogen or together form a double bond, A is C3-C7cycloalkyl which is unsubstituted or substituted once or twice by C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy, C1-C6alkylcarbonyloxy, C2-C6alkenyl, =0 or =N-R10, or A is cyclohexyl substituted once, at the 4-position, by one (C3-C6cycloalkyl)methoxy, C3-C6cycloalkyloxy, C2-C5alkenyl-CH2-oxy, or benzyloxy substituent, or A is decahydro-1-naphthyl or decahydro-2-naphthyl, or A is optionally substituted phenyl, and G is hydrogen or an agriculturally acceptable metal, sulfonium, ammonium or a latentiating group.

Hexamethylenetetramine-bromine complex (HMTAB) on wet silica: Oxidation of alcohols and sulfides

Secondary or benzylic alcohols and sulfides are converted into their corresponding carbonyl and sulfoxide compounds efficiently using wet silica supported HMTAB complex at room temperature.