(1r,4r)-4-Methoxycyclohexane-1-carboxylic acid

Base Information

Chemical Name:(1r,4r)-4-Methoxycyclohexane-1-carboxylic acid
CAS No.:73873-61-7
Molecular Formula:C8H14O3
Molecular Weight:158.197
Hs Code.:
Mol file:73873-61-7.mol

Synonyms:trans-4-Methoxy-cyclohexancarbonsaeure;4-Methoxy-cyclohexanecarboxylic acid;4-methoxycyclohexanecarboxylic acid;

Suppliers and Price of (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
trans-4-Methoxycyclohexanecarboxylicacid 95+%
1g
$ 216.00

Chemenu
trans-4-Methoxycyclohexanecarboxylicacid 95%
1g
$ 234.00

Chemenu
trans-4-Methoxycyclohexanecarboxylicacid 95%
5g
$ 701.00

Ambeed
trans-4-Methoxycyclohexanecarboxylicacid 97%
5g
$ 359.00

Ambeed
trans-4-Methoxycyclohexanecarboxylicacid 97%
1g
$ 100.00

Ambeed
trans-4-Methoxycyclohexanecarboxylicacid 97%
250mg
$ 40.00

Ambeed
trans-4-Methoxycyclohexanecarboxylicacid 97%
100mg
$ 23.00

Total 21 raw suppliers

Chemical Property of (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid

Chemical Property:

Melting Point:56 - 59 °C (petroleum ether)
PSA：46.53000
LogP:1.27620
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

trans-4-Methoxycyclohexanecarboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses trans-4-Methoxycyclohexanecarboxylic Acid is used as a reactant in the preparation of pyrazolylmethylamino isoindoline diones as cereblon binders for degradation of Ikaros useful in treatment of diseases.

Technology Process of (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid

There total 6 articles about (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-09-4
4-methoxybenzoic acid

: 73873-59-3
4-methoxycyclohexanecarboxylic acid

: 73873-61-7
trans-4-methoxycyclohexane-1-carboxylic acid

Guidance literature:: With hydrogen; In 1,4-dioxane; at 20 ℃; under 760.051 Torr; Overall yield = 27 percent; Optical yield = 72 percent de; chemoselective reaction;
DOI:10.1039/d1ob01197a

Reference yield:

: 121-98-2
methyl 4-methoxybenzoate

: 73873-61-7
trans-4-methoxycyclohexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Raney nickel; ethanol / Hydrogenation

2: aqueous methanol. KOH

With potassium hydroxide; ethanol; nickel;
DOI:10.1021/ja01569a030