3669-46-3Relevant articles and documents
1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS
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Page/Page column 61, (2010/01/30)
1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
Fries Rearrangement of ortho- and para-Methoxy Phenyl Acetates. The formation of Ketoesters
Martin, Robert,Gros, Nicole,Boehmer, Volker,Kaemmerer, Hermann
, p. 81 - 92 (2007/10/02)
During the Fries rearrangement of o- and p-methoxy phenyl acetates with AlCl3 in nitromethane at 20 deg C substitution occurs mainly in the p-position of the phenolic residue to yield p-acylphenols.Larger quantities of o-acylphenols are obtained only, if