7391-58-4

Usage

Uses

Used in Pharmaceutical and Agrochemical Production:
Butylmalononitrile is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, leveraging its reactivity and versatility to facilitate the production of these compounds.
Used in Organic Synthesis:
As a building block in organic synthesis, Butylmalononitrile is used in the preparation of heterocyclic compounds, contributing to the development of novel chemical entities.
Used in Chemical Reactions:
Butylmalononitrile is employed in a wide range of chemical reactions such as Knoevenagel condensation, Michael addition, and nucleophilic addition, demonstrating its utility in diverse synthetic pathways.
Used in the Development of Photoluminescent Materials:
Butylmalononitrile is utilized in the research and development of photoluminescent materials, indicating its potential applications in optoelectronic and sensor technologies.
Used as a Precursor for Dyes and Pigments:
Butylmalononitrile serves as a precursor in the synthesis of various dyes and pigments, contributing to the coloration and decoration of a variety of products.
Used in Medicinal Chemistry for Antimicrobial and Anti-inflammatory Properties:
Due to its potential antimicrobial and anti-inflammatory properties, Butylmalononitrile is a subject of interest in medicinal chemistry, with potential applications in the development of new therapeutic agents.

Upstream product

• 22085-89-8 butyl propanediamide 
• 1885-22-9 bromomalononitrile 
• 122-56-5 tributyl borane 
• 89851-67-2 2-(n-Butyl)cyanoacetamide 
• 542-69-8 1-iodo-butane 
• 109-77-3 malononitrile 
• 133-08-4 diethyl butylmalonate 
• 123-72-8 butyraldehyde 
• 109-65-9 1-bromo-butane 
• 75-36-5 acetyl chloride 

Downstream Products

• 4086-51-5 5-butyl-2,4,6-triaminopyrimidine 
• 62679-52-1 2,2-dicyanohexanenitrile 
• 529508-27-8 2-benzyl-2-butyl-malononitrile 
• 120634-26-6 4-Butyl-1-phenyl-1H-pyrazole-3,5-diamine 
• 79801-91-5 2-amino-3-butyl-9H-pyrido<2,3-b>indole 

Relevant academic research and scientific papers

Radical trifunctionalization of hexenenitrile via remote cyano migration

A novel radical-mediated trifunctionalization of hexenenitriles via the strategy of remote functional group migration is disclosed. A portfolio of functionalized hexenenitriles are employed as substrates. After difunctionalization of the unactivated alken

Nano-K2CO3: Preparation, characterization and evaluation of reactive activities

A novel base, nano-K2CO3, was easily prepared by ultrafine wet milling. The surface properties and the reactive activities of nano-K2CO3 were characterized. It was found that such a base showed higher basicity than normal K2CO3 and could replace sodium (or potassium) alkoxide to carry out monoalkylation and oximation of active methylene compounds. The nano-K2CO3 could be regenarated and reused 10 times without loss of its reactive activity.

Sodium borohydride as the only reagent for the efficient reductive alkylation of malononitrile with ketones and aldehydes

An efficient and convenient method for the synthesis of primary and secondary monosubstituted malononitriles has been developed. In this method, sodium borohydride in isopropanol has a catalytic effect on the initial condensation between malononitrile and

MALONONITRILE COMPOUND AND USE THEREOF AS PESTICIDES

The present invention relates to a novel malononitrile compound represented by the formula (A): wherein, R1 represents C1 to C6 alkyl that may be substituted with halogen, C2 to C6 alkenyl that may be substituted with halogen, etc; R2 represents hydrogen atom or C1 to C6 alkyl that may be substituted with halogen; R3 represents hydrogen atom or C1 to C6 alkyl; R4 represents hydrogen atom or C1 to C6 alkyl; R5 represents C1 to C6 alkyl that may be substituted with halogen, C3 to C6 alkenyl that may be substituted with halogen, etc , or R4 and R5 may be combined at their terminal and represent ethylene that may be substituted with C1 to C3 alkyl or trimethylene that may be substituted with C1 to C3 alkyl; and Z1 and Z2, which are the same or different, represent oxygen atom or sulfur atom. The malononitrile compound has an efficient pesticidal activity and can control effectively pests such as insect pests, acarine pests, nematode pests and the like.

A facile method for the construction of highly substituted acetonitriles and olefins. Malononitriles as acetonitrile carbanion and alkylidene dianion equivalents

The use of malononitrile to facilitate the preparation of highly substituted nitriles, via reductive alkylation/addition, and olefins, via a combination of reductive addition and reductive elimination, is described.

Phase Transfer Catalysis without Solvent: Selective Mono- or Di-alkylation of Malononitrile

Monoalkyl and symmetrical or unsymmetrical dialkylmalononitriles have been prepared selectively by phase transfer catalysis in the absence of solvent.Exclusive formation of a particular compound is achieved in all cases except for benzylmalononitrile 2f (79percent) and prop-2-ynylmalononitrile 2g (62percent).

Translocative Rearrangements. Generality of the Formamidine-Induced Rearrangement of 4-Substituted 5-Amino-4-cyano-4H-imidazoles

The generality of two different courses of cyclisation reactions for 4-substituted 5-amino-4-cyano-4H-imidazoles (5) is demonstrated.One results from treatment of 5 with formamidine in a "translocative rearrangement" that leads to 8-substituted 4-aminoimi