73931-44-9

Upstream product

• 634-89-9 1,2,3,5-tetrabromobenzene 
• 124-41-4 sodium methylate 
• 95970-06-2 2,3,6-tribromo-4-methoxyaniline 
• 104-94-9 4-methoxy-aniline 
• 74137-36-3 3,5-dibromoanisole 

Downstream Products

• 1006593-88-9 C₈H₆Br₂O₃ 
• 1006593-85-6 C₈H₆Br₂O₃ 

Relevant academic research and scientific papers

A study on the metalation of alkoxydibromobenzenes

The metalation of (quasi)alkoxy-substituted dibromobenzenes C 6H3(OR)Br2 with lithium diisopropylamide (LDA) has been investigated. For 1-(quasi)alkoxy-3,5-dibromobenzenes (R = Me, TMS), different selectivities were observ

POLYBROMINATED AROMATIC COMPOUNDS. IV. METHOXYDEBROMINATION REACTIONS OF POLYBROMOBENZENES IN PYRIDINE

The rates were measured and the orientation was studied for the methoxydebromination of all polybromobenzenes C6HnBr6-n (n = 0-3) in pyridine at 115 deg C.From comparison of the partial rates of substitution of the bromine atom at various positions of the benzene ring it was found that the activating effect of the bromine atom in relation to the point of nucleophilic attack changes in the order o-Br > m-Br > p-Br, and the directing selectivity of the bromine is low (compared with fluorine in the methoxydefluorination of polyfluorobenzenes) and increases with decrease in the number of bromine atoms in the aromatic ring of the substrate.

POLYBROMINATED AROMATIC COMPOUNDS. III. SYNTHESIS OF BROMINE-SUBSTITUTED ANISOLES

Reliable methods were developed for the synthesis of di-, tri-, and tetrabromoanisoles, and all the possible individual isomers were synthesized.The structures of the isomers were proved by alternative synthesis and spectral methods (PMR, IR).It was shown that the published data are incorrect in a number of cases; either the final product was assigned the incorrect structure, or the published methods led to mixture of the various isomers.