73974-68-2Relevant academic research and scientific papers
An oxyanion-Hole selective serine protease inhibitor in complex with trypsin
Cui, Jian,Marankan, Fatima,Fu, Wentao,Crich, David,Mesecar, Andrew,Johnson, Michael E
, p. 41 - 46 (2002)
p-amidinophenylmethylphosphinic acid (AMPA) was designed, synthesized and crystallized in complex with trypsin to study interactions with the oxyanion hole at the SI site. In comparison to benzamidine, AMPA shows improved activity, which the crystal struc
