66854-76-0Relevant academic research and scientific papers
The Formation of P-C Bonds Utilizing Organozinc Reagents for the Synthesis of Aryl- A nd Heteroaryl-Dichlorophosphines
Kirst, Christin,Tietze, Jonathan,Ebeling, Marian,Horndasch, Lukas,Karaghiosoff, Konstantin
, p. 17337 - 17343 (2021/11/18)
Aryl- A nd heteroaryl-dichlorophosphines are mildly and selectively made in a one-pot synthesis in moderate to good yields starting from the respective aryl bromides or five-membered heterocycles, following lithiation with nBuLi, transmetalation with ZnCl
An oxyanion-Hole selective serine protease inhibitor in complex with trypsin
Cui, Jian,Marankan, Fatima,Fu, Wentao,Crich, David,Mesecar, Andrew,Johnson, Michael E
, p. 41 - 46 (2007/10/03)
p-amidinophenylmethylphosphinic acid (AMPA) was designed, synthesized and crystallized in complex with trypsin to study interactions with the oxyanion hole at the SI site. In comparison to benzamidine, AMPA shows improved activity, which the crystal struc
