7398-82-5

Usage

Uses

Used in Chemical Industry:
Alpha, alpha, alpha', alpha'-Tetrachloro-p-xylene is used as a reactant for the production of other chemical compounds, contributing to the synthesis of various organic compounds.
Used in Organic Synthesis:
Alpha, alpha, alpha', alpha'-Tetrachloro-p-xylene is used as a key component in organic synthesis, playing a crucial role in the creation of new chemical entities.

InChI:InChI=1/C8H6Cl4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4,7-8H

Upstream product

• 106-42-3 para-xylene 
• 7782-50-5 chlorine 
• 77072-05-0 4-dichloromethyl benzaldehyde 
• 623-27-8 terephthalaldehyde, 

Downstream Products

• 623-27-8 terephthalaldehyde, 
• 909006-03-7 α,α-dichloro, α',α'-difluoro-p-xylene 
• 369-54-0 p-bis(difluoromethyl)benzene 
• 17557-10-7 α,α,α',α'-tetrakis(trimethylsilyl)-1,4-xylol 
• 55591-48-5 1,4-bis(dimorpholinomethyl)benzene 

Relevant academic research and scientific papers

Formamide Catalysis Facilitates the Transformation of Aldehydes into Geminal Dichlorides

Herein, a novel method for the transformation of aldehydes into geminal dichlorides based on phthaloyl chloride as reagent and N -formylpyrrolidine as Lewis base catalyst is disclosed. Given the mild reaction conditions, the current protocol is distinguished by high levels of functional group compatibility and scalability and is operationally simple. The in situ formation of a Vilsmeier Haack reagent type intermediate is likely to be essential for this organocatalytic nucleophilic substitution reaction.

Facile synthesis of hypercrosslinked resin via photochlorination of p-xylene and succedent alkylation polymerization

A combination of photochlorination of p-xylene and succedent Friedel-Crafts alkylation polymerization was firstly used in the preparation of the hypercrosslinked adsorptive resin. The data of GC-MS and GC showed that a series of chlorizates were produced when p-xylene was photochlorinated. Hypercrosslinked resins could be synthesized by copolymerization, self-polymerization of chlorizates or post crosslinking reaction. The chemical structure and micromorphology of the porous resins were characterized by BET, FT-IR, SEM and elementary analysis (EA). The results showed that the novel adsorptive resins possess high BET surface near to 1038 m2/g and large pore volumes range from 0.5 to 1.2 cm3/g.

METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE

A synthesis method of α,α,α′,α′-tetrachloro-p-xylene is disclosed. The method includes reacting terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing α,α,α′,α′-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde as a side product, which can be separated by silica column chromatography.

Method for the preparation of alpha, alpha, alpha', alpha' -tetrachloro-p-xylene with high purity

A method of synthesizing a high purity product of α, α, α′, α′-tetrachloro-p-xylene is disclosed. The method includes carrying out a first stage reaction of terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing α, α, α′, α′-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde as a side product; adding SOCl2 and DMF to the product mixture of the first stage reaction to undergo a second stage reaction; and to a cool water adding the resulting product mixture from the second stage reaction to obtain a solid product of α, α, α′, α′-tetrachloro-p-xylene with a purity of 90-99 mol %.

Conversion of aromatic aldehydes to gem-dichlorides using boron trichloride. A new highly efficient method for preparing dichloroarylmethanes

The chlorination of aromatic aldehydes with boron trichloride in hexane under reflux conditions produces the corresponding dichloromethyl derivatives in excellent yields. (C) 2000 Elsevier Science Ltd.

A simple and efficient procedure for the preparation of benzal chlorides and benzal bromides

Benzal chlorides and benzal bromides were conveniently synthesized by reaction of aryl aldehydes with a Vilsmeier type reagent formed in situ by reduction of CCl4 or CBr4 in dimethylformamide (DMF) as solvent.