73995-77-4

Upstream product

• 53539-02-9 methyl 3α-hydroxy-2β-(benzyloxymethyl)-4-cyclopentene-1α-acetate 
• 78-39-7 Triethyl orthoacetate 
• 41787-51-3 3α-hydroxy-2β-(benzyloxymethyl)-4-cyclopentene-1α-acetic acid 

Downstream Products

• 73995-74-1 7-oxo-2β-benzyloxymethyl-3-bicyclo<3.3.0>octene 
• 73996-31-3 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane tetrahydropyranyl ether (α-isomer) 
• 73996-36-8 3α-hydroxy-4β-bromo-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane 
• 73996-37-9 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane (α-isomer) 
• 69609-77-4 carbacyclin 
• 69552-55-2 (5E)-6a-carbaprostaglandin I₂ methyl ester 
• 82259-29-8 3α-hydroxy-4β-bromo-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane benzoate 
• 69552-46-1 (5E)-carba-PGI2 
• 71884-06-5 (5E,16R)-6α-carbaprostaglandin I₂ methyl ester 

Relevant academic research and scientific papers

Facile synthesis of 6a-carbaprostaglandin I2

The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.

6,9-Methano-PGI2 analogues

Prostaglandin I2 analogues of the formula: STR1 [wherein the symbol between the carbon atoms in positions 5 and 6 represents a single or double bond, Y represents ethylene or trans-vinylene, R1 represents hydrogen, alkyl of 1 to 12 c

Facile synthesis of 6a-carbaprostaglandin I2

The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.