740-69-2

Basic information

• Product Name: Hydrazine, 1,2-bis[4-(trifluoromethyl)phenyl]-
• CAS NO: 740-69-2
• Molecular Formula: C14H10F6N2
• Molecular Weight: 320.237
• Mol File: 740-69-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Hydrazine, 1,2-bis[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1,2-bis[4-(trifluoromethyl)phenyl]-(740-69-2)
• EPA Substance Registry System: Hydrazine, 1,2-bis[4-(trifluoromethyl)phenyl]-(740-69-2)

Safety Data

• Hazardous Substances Data: 740-69-2(Hazardous Substances Data)

Upstream product

• 402-54-0 p-nitrobenzotrifluoride 
• 98217-62-0 (E)-1,2-bis(4-(trifluoromethyl)phenyl)diazene 
• 591-19-5 m-Bromoaniline 
• 63213-03-6 1,2-bis(3-bromophenyl)diazene 
• 455-14-1 4-trifluoromethylphenylamine 
• 34913-29-6 4,4′-bis(trifluoromethyl)azobenzene 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 98217-62-0 (E)-1,2-bis(4-(trifluoromethyl)phenyl)diazene 
• 34913-29-6 4,4′-bis(trifluoromethyl)azobenzene 
• 455-14-1 4-trifluoromethylphenylamine 

Relevant articles and documents

Visible-Light-Promoted Diboron-Mediated Transfer Hydrogenation of Azobenzenes to Hydrazobenzenes

A visible-light-promoted transfer hydrogenation of azobenzenes has been developed. In the presence of B2pin2 and upon visible-light irradiation, the reactions proceeded smoothly in methanol at ambient temperature. The azobenzenes with diverse functional groups have been reduced to the corresponding hydrazobenzenes with a yield of up to 96%. Preliminary mechanistic studies indicated that the hydrogen atom comes from the solvent and the transformation is achieved through a radical pathway.

Electrochemical formation of: N, N ′-diarylhydrazines by dehydrogenative N-N homocoupling reaction

Hydrazines represent a class of compounds of high interest due to their applicability as versatile starting materials in many important transformations. Herein, we report a synthetic approach to hydrazine derivatives using commercially available anilines and an anodic dehydrogenative N-N coupling reaction as the key step.

Visible-light-promoted oxidative dehydrogenation of hydrazobenzenes and transfer hydrogenation of azobenzenes

Azo compounds are widely used in the pharmaceutical and chemical industries. Here, we report the use of a non-metal photo-redox catalyst, Eosin Y, to synthesize azo compounds from hydrazine derivatives. The use of visible-light with air as the oxidant makes this process sustainable and practical. Moreover, the visible-light-driven, photo-redox-catalyzed transfer hydrogenation of azobenzenes is compatible with a series of hydrogen donors such as phenyl hydrazine and cyclic amines. Compared with traditional (thermal/transition-metal) methods, our process avoids the issue of over-reduction to aniline, which extends the applicability of photo-redox catalysis and confirms it as a useful tool for synthetic organic chemistry.