74032-48-7

Upstream product

• 2127-03-9 2,2'-dipyridyldisulphide 
• 100-09-4 4-methoxybenzoic acid 
• 2637-34-5 2-Sulfanylpyridine 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 833-79-4 t-butyl 4-methoxybenzoate 
• 665005-96-9 1-(4-methoxybenzoyl)-5-(4-methoxyphenyl)dipyrromethane 
• 852244-64-5 1-(4-methoxybenzoyl)-5-phenyldipyrromethane 
• 345-89-1 4-fluoro-4'-methoxybenzophenone 
• 55234-56-5 4-(4-methoxy-phenyl)-4-oxo-butyronitrile 
• 1051917-95-3 5-(4-tert-butylphenyl)-1-(4-methoxybenzoyl)dipyrromethane 
• 1026585-07-8 (4-methoxy-phenyl)-{5-[pentafluorophenyl-(1H-pyrrol-2-yl)-methyl]-1H-pyrrol-2-yl}-methanol 
• 262267-46-9 1-(4-methoxybenzoyl)-5-(pentafluorophenyl)dipyrromethane 
• 90-96-0 bis(p-methoxyphenyl)methanone 

Relevant academic research and scientific papers

Cobalt-catalyzed acylation-reactions of (hetero)arylzinc pivalates with thiopyridyl ester derivatives

A cobalt-catalyzed acylation reaction of various primary, secondary and tertiary alkyl, benzyl and (hetero)aryl S-pyridyl thioesters with (hetero)arylzinc pivalates is reported. The thioesters were prepared directly from the corresponding carboxylic acids under mild conditions, thus tolerating sensitive functional groups. Acylations of α-chiral S-pyridyl esters proceeded with very high stereoretention leading to optically enriched α-chiral ketones.

Facile synthesis of 1,9-diacyldipyrromethanes

The present invention provides a method of making a metal complex. The method comprises the steps of: (a) acylating a dipyrromethane or a 1-monoacyldipyrromethane to form a mixed reaction product comprising a 1,9-diacyidipyrromethane; (b) combining the re

9-Acylation of 1-acyldipyrromethanes containing a dialkylboron mask for the α-acylpyrrole motif

1,9-Diacyldipyrromethanes are important precursors to porphyrins, yet synthetic access remains limited owing to (1) poor conversion in the 9-acylation of 1-acyldipyrromethanes and (2) handling difficulties because acyldipyrromethanes typically streak upon

Efficient synthesis of monoacyl dipyrromethanes and their use in the preparation of sterically unhindered trans-porphyrins

The condensation of an aldehyde with a dipyrromethane bearing a sterically unhindered aryl substituent at the 5-position typically results in low yield and a mixture of porphyrin products derived from acidolytic scrambling. We have developed a concise nonscrambling synthesis of such trans-porphyrins that takes advantage of the availability of multigram quantities of dipyrromethanes. This route involves the selective monoacylation of the dipyrromethanes with a pyridyl thioester, reduction of the monoacyl dipyrromethane to the corresponding carbinol, and self- condensation of the carbinol to form the porphyrin. The monoacylation procedure has wide scope as demonstrated by the preparation of a set of 15 diverse monoacyl dipyrromethanes in good yield at the multigram scale. The dipyrromethanecarbinol self-condensation reaction is extremely rapid (3 min) under mild room-temperature conditions and affords the trans-porphyrin in 16- 28% yield. Analysis by laser-desorption mass spectrometry (LD-MS) of samples from the crude reaction mixture revealed no scrambling within the limit of detection (1 part in 100). The self-condensation is compatible with a range of electron-withdrawing or -releasing substituents as well as substituents for building block applications (TMS-ethyne, ethyne, iodo, ester). The absence of any detectable scrambling in the self-condensation enables a simple purification. The synthesis readily affords gram quantities of pure, sterically unhindered trans-porphyrins in a process involving minimal chromatography.