74080-58-3

Basic information

• Product Name: methyl 3α-hydroxy-2β-(benzyloxymethyl)-5-(carbomethoxymethylene)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether
• Synonyms: methyl 3α-hydroxy-2β-(benzyloxymethyl)-5-(carbomethoxymethylene)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether
• CAS NO: 74080-58-3
• Molecular Weight: 432.514
• Mol File: 74080-58-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 3α-hydroxy-2β-(benzyloxymethyl)-5-(carbomethoxymethylene)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3α-hydroxy-2β-(benzyloxymethyl)-5-(carbomethoxymethylene)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether(74080-58-3)
• EPA Substance Registry System: methyl 3α-hydroxy-2β-(benzyloxymethyl)-5-(carbomethoxymethylene)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether(74080-58-3)

Safety Data

• Hazardous Substances Data: 74080-58-3(Hazardous Substances Data)

Upstream product

• 82259-28-7 [(4S,5R)-4-Benzyloxymethyl-2-oxo-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-6a-yl]-trimethylsilanyl-acetic acid methyl ester 
• 186581-53-3 diazomethane 
• 67-56-1 methanol 
• 74028-40-3 [(1R,2S,3R)-2-Benzyloxymethyl-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-acetic acid methyl ester 
• 74028-39-0 [(1R,2S,3R)-2-Benzyloxymethyl-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-acetic acid 
• 74163-85-2 methyl 3α-hydroxy-5-oxo-2β-(benzyloxymethyl)cyclopentane-1α-acetate 3-tetrahydropyran-2-yl ether 
• 32233-38-8 3α,5α-dihydroxy-2β-(benzyloxymethyl)cyclopentane-1α-acetic acid γ-lactone 3-tetrahydropyran-2-yl ether 
• 2916-76-9 methyl (trimethylsilyl)acetate 

Downstream Products

• 73995-84-3 methyl 3α-hydroxy-2β-(benzyloxymethyl)-5ξ-(carbomethoxymethyl)cyclopentane-1ξ-acetate tetrahydropyran-2-yl ether 
• 74028-42-5 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane tetrahydropyranyl ether (β-isomer) 
• 73996-31-3 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane tetrahydropyranyl ether (α-isomer) 
• 82293-07-0 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane (β-isomer) 
• 69609-77-4 carbacyclin 
• 69552-55-2 (5E)-6a-carbaprostaglandin I₂ methyl ester 
• 69552-46-1 (5E)-carba-PGI2 
• 71884-06-5 (5E,16R)-6α-carbaprostaglandin I₂ methyl ester 

Relevant articles and documents

Facile synthesis of 6a-carbaprostaglandin I2

The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.

Facile synthesis of 6a-carbaprostaglandin I2

The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.