740805-29-2

Upstream product

• 766-94-9 vinyl phenyl ether 
• 740805-26-9 (3S,4R,5S)-3,4-isopropylidenedioxy-5-methyl-1-pyrroline-N-oxide 
• 1314088-68-0 5-deoxy-2,3-O-isopropylidene-1,4-di-O-methanesulfonyl-D-ribitol 
• 1314088-69-1 1,4,5-trideoxy-N-hydroxy-1,4-imino-2,3-O-isopropylidene-L-lyxitol 
• 1314088-64-6 benzyl 5-bromo-5-deoxy-2,3-O-isopropylidene-β-D-ribofuranoside 
• 117557-98-9 (1R)-1-((4R,5S)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane-4-yl)ethan-1-ol 
• 589-10-6 phenoxyethyl bromide 
• 158112-53-9 (3aR,6R,6aR)-2,2,6-trimethyltetrahydro-2H-furo(3,4-d)(1,3)dioxol-4-ol 
• 75100-21-9 benzyl 5-deoxy-2,3-O-isopropylidene-β-D-ribofuranoside 
• 23276-32-6 benzyl 2,3-O-isopropylidene-D-ribofuranoside 

Downstream Products

• 740805-33-8 phenyl (2S,3S,4R,5S)-1-benzyl-5-methyl-3,4-isopropylidenedioxypyrrolidine-2-acetate 
• 740805-34-9 (2S,3S,4R,5S)-1-benzyl-3,4-isopropylidenedioxy-5-methylpyrrolidinemethylpyrrolidine-2-ethanol 
• 740805-35-0 2-((3aS,4S,6S,6aR)-5-Benzyl-2,2,6-trimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrol-4-yl)-N-hydroxy-acetamide 
• 1314088-79-3 (2S,3aS,4S,5R,6S)-6-methyl-2-phenoxyhexahydropyrrolo[1,2-b]isoxazole-4,5-diol 

Relevant academic research and scientific papers

Nitrone in L-lyxose series: Cycloaddition way for the synthesis of new C-α-fucosides

Nitrone 3 analogue of 5-deoxy-L-lyxose was derived from D-ribose. Its reduction with aqueous SO2 gave the corresponding 4-amino-sugar 2, a potent α-L-fucosidase inhibitor. 1,3-Dipolar cycloaddition of 3 with alkenes allowed the synthesis of ace

Synthesis of 4-amino-4,5-dideoxy-L-lyxofuranose derivatives and their evaluation as fucosidase inhibitors

The nitrone 4 (4,5-dideoxy-4-hydroxylamino-3,4-O-isopropylidene-L- lyxofuranose) was synthesised from d-ribose and used as key intermediate for the preparation of fucosidase inhibitors. We describe two transformations of 4. Hydrolysis with aqueous sulfur